| Category |
Oncology |
| Manuscript Type |
Minireviews |
| Article Title |
Primary melanoma of the gastrointestinal tract
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Paola De Nardi, Stefania Guida, Giuseppe Damiano, Nathalie Rizzo, Ana Maria Samanes Gajate, Silvia Teresa Riva, Giovanni Paolino, Michele Colombo, Roberta Tummineri, Franco Rongioletti, Santo Raffaele Mercuri, Arturo Chiti, Pierpaolo Sileri and Vincenzo Russo |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Paola De Nardi, FASCRS, MD, Department of Colorectal Surgery, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, Milan 20132, Italy. denardi.paola@hsr.it |
| Key Words |
Gastrointestinal melanoma; Mucosal melanoma; Anorectal melanoma; Gastric melanoma; Esophageal melanoma |
| Core Tip |
Gastrointestinal primary melanomas are very rare, with literature comprised of isolated case reports and small series. Compared with cutaneous melanoma, they display distinct molecular profiles, more aggressive clinical behavior, poorer prognoses with less favorable response to systemic therapy. These tumors have been poorly researched, and, because of their rarity, development of standardized management has been delayed. The present review shows all the relevant domains, including epidemiology, etiology, molecular features, diagnosis, and therapy, offering a general profile of this challenging and poorly studied disease. |
| Citation |
De Nardi P, Guida S, Damiano G, Rizzo N, Samanes Gajate AM, Riva ST, Paolino G, Colombo M, Tummineri R, Rongioletti F, Mercuri SR, Chiti A, Sileri P, Russo V. Primary melanoma of the gastrointestinal tract. World J Gastroenterol 2026; In press |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
