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Publication Name World Journal of Stem Cells
Manuscript ID 114891
Country China
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Co-expression of cancer stem cell markers CD24 and CD133 in gastric cancer tissues: Clinicopathological and prognostic significance
Manuscript Source Unsolicited Manuscript
All Author List Cheng-Xian Ma, Jie Chen, Jian-Lin Wang, Shuai Pei, Zhao-Jun Zhang, Yu-Si Xie and Xia He
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 82003223
China Postdoctoral Science Foundation 2020M671398
Corresponding Author Xia He, Full Professor, Department of Oncology, The Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, No. 42 Baiziting, Kunlun Road, Nanjing 210009, Jiangsu Province, China. hexiabm@163.com
Key Words Gastric cancer; CD24; CD133; Cancer stem cell; Co-expression; Prognosis; Immunohistochemistry
Core Tip CD24 and CD133 exhibit high positive detection rates in gastric cancer tissues. The co-expression of CD24 and CD133 was closely related to the advanced tumor stage. Co-positivity of CD24 and CD133 predicts poor survival. The co-expression of CD24/CD133 may reflect the higher invasive and metastatic potential of gastric cancer. This combined indicator can be used as a potential prognostic marker and direction for targeted therapeutic strategies.
Citation Ma CX, Chen J, Wang JL, Pei S, Zhang ZJ, Xie YS, He X. Co-expression of cancer stem cell markers CD24 and CD133 in gastric cancer tissues: Clinicopathological and prognostic significance. World J Stem Cells 2025; In press
Received
2025-10-14 09:12
Peer-Review Started
2025-10-14 09:12
First Decision by Editorial Office Director
2025-10-28 09:40
Return for Revision
2025-10-28 09:40
Revised
2025-10-29 15:56
Publication Fee Transferred
Second Decision by Editor
2025-11-25 02:46
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-03 09:32
Articles in Press
2025-12-03 09:32
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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