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Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 115285
Country Spain
Category Surgery
Manuscript Type Meta-Analysis
Article Title Staging laparoscopy in esophagogastric junction cancer: Systematic review and meta-analysis
Manuscript Source Invited Manuscript
All Author List Roberto de la Plaza Llamas, Diego Ribera Díaz, Paula Betancor Díaz, Daniel A Díaz Candelas, Raquel A Latorre-Fragua, Ludovica Gorini, Rodrigo Arellano González and Ignacio A Gemio del Rey
Funding Agency and Grant Number
Corresponding Author Roberto de la Plaza Llamas, Associate Professor, Chief Physician, FACS, Head, MD, PhD, Department of Surgery, Medical and Social Sciences, Faculty of Medicine and Health Sciences, Universidad de Alcalá, Campus Universitario - C/ 19, Av. de Madrid, Km 33600, Alcalá de Henares 28871, Madrid, Spain. roberto.plaza@uah.es
Key Words Esophagogastric junction; Laparoscopy; Neoplasm staging; Staging laparoscopy; Systematic review; Meta-analysis
Core Tip Staging laparoscopy (SL) upstaged nearly one in five patients with clinically resectable gastroesophageal junction cancer by revealing occult peritoneal or hepatic metastases. This finding underlines the value of SL in refining staging and guiding treatment decisions. Diagnostic performance was especially high in Siewert II tumors, without any significant heterogeneity. However, key procedural and patient-related data were not appropriately reported across studies. These results support the routine use of SL in staging gastroesophageal junction tumors and highlight the urgent need for standardized reporting to improve risk stratification and clinical outcomes in this challenging and heterogeneous cancer subgroup.
Citation de la Plaza Llamas R, Ribera Díaz D, Betancor Díaz P, Díaz Candelas DA, Latorre-Fragua RA, Gorini L, Arellano González R, Gemio del Rey IA. Staging laparoscopy in esophagogastric junction cancer: Systematic review and meta-analysis. World J Gastrointest Surg 2025; In press
Received
2025-10-15 02:15
Peer-Review Started
2025-10-15 02:15
First Decision by Editorial Office Director
2025-10-24 10:50
Return for Revision
2025-10-24 10:50
Revised
2025-10-29 17:25
Publication Fee Transferred
Second Decision by Editor
2025-12-04 02:33
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-04 06:18
Articles in Press
2025-12-04 06:18
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
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