Publication Name	World Journal of Gastrointestinal Pathophysiology
Manuscript ID	115307
Country	United States

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	From esophagus to colon: A narrative review of eosinophilic gastrointestinal disorders
Manuscript Source	Invited Manuscript
All Author List	Abeer Qasim, George S Zacharia, FNU Veena, Sameer D Kandhi and Harish Patel
Funding Agency and Grant Number
Corresponding Author	George S Zacharia, Academic Fellow, DM, MD, Department of Internal Medicine, BronxCare Health System, 1650 Grand Concourse, Bronx, NY 10457, United States. george.lenx@yahoo.com
Key Words	Eosinophilic; Gastrointestinal diseases; Esophagitis; Gastritis; Gastroenteritis; Colitis; Proton pump inhibitors
Core Tip	Eosinophilic gastrointestinal disorders encompass a spectrum of chronic, immune-mediated conditions characterized by eosinophilic infiltration of the gastrointestinal tract in the absence of secondary causes. Despite its increasing prevalence, significant gaps remain in awareness, diagnosis, and treatment of the disease. The diagnosis mandates demonstration of tissue eosinophilia, typically on gastrointestinal endoscopic biopsies, together with exclusion of secondary causes. The treatment involves dietary modifications, corticosteroids, proton pump inhibitors, and emerging biologics targeting key cytokine pathways. The lack of standardized guidelines emphasizes the need for multidisciplinary care and further research to refine diagnostic thresholds and optimize treatment strategies.
Citation	Qasim A, Zacharia GS, Veena F, Kandhi SD, Patel H. From esophagus to colon: A narrative review of eosinophilic gastrointestinal disorders. World J Gastrointest Pathophysiol 2026; In press

Received	2025-10-16 13:21
Peer-Review Started	2025-10-16 13:22
First Decision by Editorial Office Director	2025-12-09 09:40
Return for Revision	2025-12-11 23:24
Revised	2025-12-17 02:12
Publication Fee Transferred
Second Decision by Editor	2026-01-27 02:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-01-27 09:02
Articles in Press	2026-01-27 09:02
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2150-5330 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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