Publication Name	World Journal of Diabetes
Manuscript ID	115495
Country	Bangladesh

Category	Endocrinology & Metabolism
Manuscript Type	Meta-Analysis
Article Title	Safety and efficacy of sodium-glucose cotransporter-2 inhibitors in adults with type 2 diabetes fasting during Ramadan: A meta-analysis
Manuscript Source	Invited Manuscript
All Author List	Abul Bashar Mohammad Kamrul-Hasan, Shehla Shaikh, Hamid Ashraf, Mohammad Shafi Kuchay, Lakshmi Nagendra, Deep Dutta and Joseph M Pappachan
Funding Agency and Grant Number
Corresponding Author	Abul Bashar Mohammad Kamrul-Hasan, Assistant Professor, Department of Endocrinology, Mymensingh Medical College, Mymensingh Sadar, Mymensingh 2200, Bangladesh. rangassmc@gmail.com
Key Words	Type 2 diabetes; Sodium-glucose cotransporter-2 inhibitors; Ramadan; Religious fasting; Safety; Meta-analysis
Core Tip	This meta-analysis assessed the safety and effectiveness of sodium-glucose cotransporter-2 inhibitors (SGLT2i) in adults with type 2 diabetes fasting during Ramadan. Among 12 studies with 3625 participants, SGLT2i increased risks of postural dizziness, hypotension, and sodium loss, but achieved greater reductions in blood pressure and a lower risk of symptomatic hypoglycemia than other glucose-lowering drugs. SGLT2i did not impact glycemic control, body weight, or renal function. Other adverse events, like dehydration and severe hypoglycemia, showed no significant difference. SGLT2i appear safe and effective for diabetes management during Ramadan fasting, but larger studies are needed to confirm safety for vulnerable groups.
Citation	Kamrul-Hasan ABM, Shaikh S, Ashraf H, Kuchay MS, Nagendra L, Dutta D, Pappachan JM. Safety and efficacy of sodium-glucose cotransporter-2 inhibitors in adults with type 2 diabetes fasting during Ramadan: A meta-analysis. World J Diabetes 2025; In press

Received	2025-10-20 00:20
Peer-Review Started	2025-10-21 08:06
First Decision by Editorial Office Director	2025-11-18 07:48
Return for Revision	2025-11-18 07:48
Revised	2025-11-26 04:17
Publication Fee Transferred
Second Decision by Editor	2025-12-29 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-30 06:13
Articles in Press	2025-12-30 06:13
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9358 (online)
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