BPG is committed to discovery and dissemination of knowledge
Articles in Press
12/5/2025 8:13:08 AM | Browse: 125 | Download: 0
Publication Name World Journal of Stem Cells
Manuscript ID 115655
Country Russia
Category Oncology
Manuscript Type Letter to the Editor
Article Title Cancer cell-dependent increase in senescence-like populations following exosome treatment: The role of extracellular matrix and cellular glycocalyx
Manuscript Source Unsolicited Manuscript
All Author List Ilya D Klabukov, Anastas Kisel, Elena Yatsenko, Yana Sulina and Denis S Baranovskii
Funding Agency and Grant Number
Funding Agency Grant Number
Russian Science Foundation 24-64-00028
Corresponding Author Ilya D Klabukov, Associate Professor, Head, PhD, Department of Regenerative Medicine, National Medical Research Radiological Center, 4 Koroleva Street, Obninsk 249036, Kaluzhskaya Oblast’, Russia. ilya.klabukov@gmail.com
Key Words Cancer; Extracellular matrix; Glycocalyx; Exosomes; Extracellular vesicles; Tumor microenvironment
Core Tip Extracellular vesicles can promote or inhibit oncogenic progression by shaping the tumor microenvironment. The efficiency of extracellular vesicle delivery can be affected by the extracellular matrix and altered glycocalyx. The tumor extracellular matrix and cellular glycocalyx can create a permissive niche for invasion, immune evasion, and metastasis. These factors are also essential for predicting the effectiveness of targeted therapies and the responses of bystander cells. Understanding these factors is crucial for treating cancers that are resistant to immunotherapies.
Citation

Klabukov ID, Kisel A, Yatsenko E, Sulina Y, Baranovskii DS. Cancer cell-dependent increase in senescence-like populations following exosome treatment: The role of extracellular matrix and cellular glycocalyx. World J Stem Cells 2026; 18(1): 115655

Received
2025-10-22 08:34
Peer-Review Started
2025-10-22 08:34
First Decision by Editorial Office Director
2025-10-29 08:31
Return for Revision
2025-10-29 08:31
Revised
2025-11-01 16:11
Publication Fee Transferred
Second Decision by Editor
2025-12-05 02:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-05 08:13
Articles in Press
2025-12-05 08:13
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-12 02:54
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com