Publication Name	World Journal of Gastrointestinal Pharmacology and Therapeutics
Manuscript ID	115729
Country	China

Category	Pharmacology & Pharmacy
Manuscript Type	Editorial
Article Title	Yiyi Fuzi Baijiang powder: A promising traditional Chinese medicine for ulcerative colitis through microecological and multi-pathway regulation
Manuscript Source	Invited Manuscript
All Author List	Shuang-Lin Qin, Guang-Shuai Zhang and Xiao-He Xiao
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China (General Program) No. 82204250 Hunan Science Fund for Distinguished Young Scholars No. 2025JJ20098
Corresponding Author	Xiao-He Xiao, National Engineering Research Center of Personalized Diagnostic and Therapeutic Technology, Research Center for Precision Medication of Chinese Medicine, FuRong Laboratory, Hunan University of Chinese Medicine, No. 300 Xueshi Road, Yuelu District, Changsha 410208, Hunan Province, China. pharmacy302@126.com
Key Words	Yiyi Fuzi Baijiang powder; Traditional Chinese medicine; Ulcerative colitis; Intestinal microecology; Network pharmacology; Inflammatory signaling pathways; Nuclear factor kappa-B
Core Tip	The therapeutic application of Yiyi Fuzi Baijiang powder for ulcerative colitis extends beyond merely altering the structure and abundance of gut microbiota. Instead, it aims to restore dynamic equilibrium by comprehensively modulating the intestinal microecological balance, thereby facilitating disease recovery. Furthermore, it is hypothesized that Yiyi Fuzi Baijiang powder may exert its effects on ulcerative colitis through potential mechanisms involving the NFKB1, RELA, and nuclear factor kappa B inhibitor alpha regulatory pathways, as well as the cancer and adipocytokine signaling pathways.
Citation	Qin SL, Zhang GS, Xiao XH. Yiyi Fuzi Baijiang powder: A promising traditional Chinese medicine for ulcerative colitis through microecological and multi-pathway regulation. World J Gastrointest Pharmacol Ther 2026; In press

Received	2025-10-24 02:51
Peer-Review Started	2025-10-24 02:52
First Decision by Editorial Office Director	2025-11-30 01:53
Return for Revision	2025-12-01 01:40
Revised	2025-12-13 13:03
Publication Fee Transferred
Second Decision by Editor	2026-03-09 02:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-03-09 07:46
Articles in Press	2026-03-09 07:46
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2150-5349 (online)
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