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Publication Name World Journal of Methodology
Manuscript ID 116058
Country Pakistan
Category Anesthesiology
Manuscript Type Systematic Reviews
Article Title Impact of different anesthetic agents (propofol, etomidate, ketamine) on seizure duration and cognitive recovery in electroconvulsive therapy
Manuscript Source Invited Manuscript
All Author List Hersh Tilokani, Inshal Jawed, Anmol Shehzadi, Asif Ali, Amna Khan, Umair Qadir, Abu Huraira Bin Gulzar, Remsha Zahid, Suleman Khan, Madho Mal, Mohammad Ali Zakeri, Hobab Aslam and Muhammad Umair Siddique
Funding Agency and Grant Number
Corresponding Author Inshal Jawed, Department of Medicine, Dow University of Health Sciences, Baba-e-urdu Karachi, Karachi 75350, Sindh, Pakistan. inshaljwd@gmail.com
Key Words Electroconvulsive therapy; Anesthesia; Propofol; Etomidate; Ketamine; Seizure duration; Cognitive recovery
Core Tip Etomidate most reliably preserves therapeutically adequate electroconvulsive therapy seizures and is associated with less short-term cognitive decline than propofol. Propofol shortens seizure duration, gives smoother recovery but faster emergence; ketamine adds antidepressant benefit yet has variable effects on seizure duration and raises blood pressure/heart rate. The choice of the agent depends on the primary clinical goal and the patient’s cardiovascular and cognitive risk profile
Citation Tilokani H, Jawed I, Shehzadi A, Ali A, Khan A, Qadir U, Bin Gulzar AH, Zahid R, Khan S, Mal M, Zakeri MA, Aslam H, Siddique MU. Impact of different anesthetic agents (propofol, etomidate, ketamine) on seizure duration and cognitive recovery in electroconvulsive therapy. World J Methodol 2026; In press
Received
2025-11-17 03:58
Peer-Review Started
2025-11-17 03:58
First Decision by Editorial Office Director
2025-11-30 01:35
Return for Revision
2025-11-30 01:35
Revised
2025-12-24 18:47
Publication Fee Transferred
Second Decision by Editor
2026-04-03 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-04-03 07:51
Articles in Press
2026-04-03 07:51
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2222-0682 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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