Publication Name	World Journal of Cardiology
Manuscript ID	116172
Country	United States

Category	Medicine, General & Internal
Manuscript Type	Systematic Reviews
Article Title	Non-traditional risk factors for myocardial infarction in adults under forty: A systematic review of emerging trends
Manuscript Source	Invited Manuscript
All Author List	Tirath Patel, Muhammad Farhan, Nehal K Bhatt, Hewaz A Fatah, Joel J Peniel, Ved V Kaulgud, Tisimol Mathew, Aashita M Bapat, Waleed SS Harazeen, Abdullatif N Alatta and Ayoola Awosika
Funding Agency and Grant Number
Corresponding Author	Ayoola Awosika, MD, Department of Family Medicine, University of Illinois College of Medicine Peoria, 1 Illini Drive, Bloomington, IL 61601, United States. ayoolaawosika@yahoo.com
Key Words	Acute myocardial infarction; Coronary artery disease; ST-elevation myocardial infarction; Young adult
Core Tip	Non-traditional risk factors such as psychosocial stressors, autoimmune disorders, biological aging and specific lifestyle and environmental exposures play a significant role in myocardial infarction risk and outcome among individuals aged < 40 years. Psychosocial factors like depression, low socioeconomic status, and unpartnered status were significantly associated with adverse events, especially among young women. Autoimmune diseases and inflammation indicators, as well as sleep disorders and unhealthy lifestyle patterns, additionally improved the risk.
Citation	Patel T, Farhan M, Bhatt NK, Fatah HA, Peniel JJ, Kaulgud VV, Mathew T, Bapat AM, Harazeen WSS, Alatta AN, Awosika A. Non-traditional risk factors for myocardial infarction in adults under forty: A systematic review of emerging trends. World J Cardiol 2026; In press

Received	2025-11-04 04:43
Peer-Review Started	2025-11-04 04:43
First Decision by Editorial Office Director	2025-11-14 06:55
Return for Revision	2025-11-14 06:55
Revised	2025-11-14 19:56
Publication Fee Transferred
Second Decision by Editor	2026-01-04 02:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-01-04 11:17
Articles in Press	2026-01-04 11:17
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1949-8462 (online)
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