Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	116336
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Observational Study
Article Title	Detection rate and risk factors of colorectal adenoma in high-altitude population: A cross-sectional study
Manuscript Source	Unsolicited Manuscript
All Author List	Xiao-Lei Zhao, Wang-Yang Chen, Yi-Meng Liu, Suo-Lang Danzeng, Qu-Zhen Pingcuo, Zhen Yu, Hong-Da Chen, Yang-Jin Ciren and Dong Wu
Funding Agency and Grant Number	Funding Agency Grant Number the Scientific Research Development Funds of Peking University People’s Hospital RDJP2022-15 the Xizang Autonomous Region Natural Science Foundation Group Medical Aid Project XZ2024ZR-ZY012(Z) Clinical Research Excellence Program for Research-Oriented Wards BRWEP2024W034010103 Science and Technology Projects of Xizang Autonomous Region, China XZ202501JD0021 Science and Technology Projects of Xizang Autonomous Region, China XZ202501ZY0072 National Key Research and Development Program of China 2024YFA0918504 Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences 2022-I2M-1-003
Corresponding Author	Dong Wu, Chief Physician, PhD, President, Professor, Department of Gastroenterology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, No. 1 Shuaifuyuan, Dongcheng District, Beijing 100730, Beijing, China. wudong@pumch.cn
Key Words	High altitude; Xizang Autonomous Region; Colorectal adenoma; Colorectal cancer; Detection rate
Core Tip	In this cross-sectional study of 1154 Tibetans, the colorectal adenoma (CRA) detection rate in the high-altitude Xizang Autonomous Region population was 7.7%. This was significantly lower than the 22.8% rate found in a rigorously matched low-altitude Beijing cohort. Advanced age and male sex were identified as the only independent risk factors for CRA in the Xizang Autonomous Region group.
Citation	Zhao XL, Chen WY, Liu YM, Danzeng SL, Pingcuo QZ, Yu Z, Chen HD, Ciren YJ, Wu D. Detection rate and risk factors of colorectal adenoma in high-altitude population: A cross-sectional study. World J Gastrointest Oncol 2025; In press

Received	2025-11-11 13:38
Peer-Review Started	2025-11-11 13:39
First Decision by Editorial Office Director	2025-11-19 11:05
Return for Revision	2025-11-19 11:17
Revised	2025-11-25 07:59
Publication Fee Transferred	2025-11-27 05:44
Second Decision by Editor	2025-12-11 02:46
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-11 07:33
Articles in Press	2025-12-11 07:33
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Typeset the Manuscript

ISSN	1948-5204 (online)
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