Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	116365
Country	Lebanon

Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Hidden intestinal angiosarcoma behind anemia during tyrosine kinase inhibitor therapy for chronic myeloid leukemia: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Tala Najdi, Samah Seif, Diana Khoury, Antony Kahwagi, Perla Wehbe, Rita Karam, Layal El Halabi, Rita Slim, Ghassan Chakhtoura, Viviane Trak and Roland Eid
Funding Agency and Grant Number
Corresponding Author	Tala Najdi, MD, Department of Hematoogy-Oncology, Hotel-Dieu de France University Hospital., Faculty of Medicine, Saint Joseph University, Beirut, Lebanon., Achrafieh, Beirut 166830, Lebanon. tala.najdi@net.usj.edu.lb
Key Words	Intestinal angiosarcoma; Epithelioid angiosarcoma; Anemia; Chronic myeloid leukemia; Tyrosine kinase inhibitor; Nilotinib; Metastasis; Case report
Core Tip	Angiosarcoma is rare and carries a poor prognosis, often presenting subtly both clinically and radiologically. In some cases, it manifests only as persistent unexplained anemia, making early recognition difficult. The tumor may remain hidden, mimicking benign lesions, with symptoms masked or altered by concurrent treatments. In patients receiving tyrosine kinase inhibitors, such as for chronic myeloid leukemia, modulation of the vascular endothelial growth factor pathway and related mechanisms can further obscure tumor behavior and distort imaging findings, contributing to diagnostic delay.
Citation	Najdi T, Seif S, Khoury D, Kahwagi A, Wehbe P, Karam R, El Halabi L, Slim R, Chakhtoura G, Trak V, Eid R. Hidden intestinal angiosarcoma behind anemia during tyrosine kinase inhibitor therapy for chronic myeloid leukemia: A case report. World J Gastrointest Oncol 2026; In press

Received	2025-11-14 12:11
Peer-Review Started	2025-11-14 12:11
First Decision by Editorial Office Director	2025-12-02 10:19
Return for Revision	2025-12-02 20:53
Revised	2025-12-05 00:38
Publication Fee Transferred
Second Decision by Editor	2026-01-04 02:47
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-01-04 08:15
Articles in Press	2026-01-04 08:15
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
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