Publication Name	World Journal of Hepatology
Manuscript ID	117018
Country	Brazil

Category	Gastroenterology & Hepatology
Manuscript Type	Correspondence
Article Title	Letter to the Editor: Steatotic liver disease in chronic hepatitis C - a marker of systemic risk, not direct-acting antiviral treatment failure
Manuscript Source	Invited Manuscript
All Author List	Abdo Imad El Tawil and Claudia Alexandra Pontes Ivantes
Funding Agency and Grant Number
Corresponding Author	Abdo Imad El Tawil, Principal Investigator, Researcher, Department of Medical Research, Faculdade Evangélica Mackenzie do Paraná, Rua Padre Anchieta 2770, Curitiba 80730-000, Paraná, Brazil. abdoieltawil@gmail.com
Key Words	Chronic hepatitis C; Direct-acting antiviral; Genotype 3; Liver cirrhosis; Steatotic liver disease; Liver fibrosis; Metabolic disfunction
Core Tip	This letter discusses the real-world findings of Janczura et al, who evaluated the impact of steatotic liver disease on chronic hepatitis C virus infection in the era of direct-acting antivirals. Their work highlights how metabolic dysfunction, aging, and genotype-specific characteristics contribute to persistent liver risk despite viral cure. By emphasizing the role of noninvasive steatosis assessment in identifying high-risk patients and guiding long-term monitoring, this correspondence reinforces the clinical relevance of steatotic liver disease in shaping the prognosis and follow-up strategies for individuals with current or past hepatitis C virus infection.
Citation	El Tawil AI, Ivantes CAP. Letter to the Editor: Steatotic liver disease in chronic hepatitis C - a marker of systemic risk, not direct-acting antiviral treatment failure. World J Hepatol 2026; In press

Received	2025-12-08 06:11
Peer-Review Started	2025-12-08 10:06
First Decision by Editorial Office Director	2026-02-06 10:20
Return for Revision	2026-02-06 10:20
Revised	2026-02-08 21:35
Publication Fee Transferred
Second Decision by Editor	2026-03-31 02:35
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-03-31 08:51
Articles in Press	2026-03-31 08:51
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5182 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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