Publication Name	World Journal of Diabetes
Manuscript ID	117243
Country	United States

Category	Physiology
Manuscript Type	Letter to the Editor
Article Title	Is the cellular attribution of liraglutide action in diabetic cardiomyopathy conclusive?
Manuscript Source	Invited Manuscript
All Author List	Ke Su, Pei-Yan Cao, Gan Chen and Ke Wu
Funding Agency and Grant Number
Corresponding Author	Ke Wu, Assistant Professor, MD, PhD, Investigator, Institute for Advanced Biomedical Research, Charles R. Drew University of Medicine and Science, 1731 E. 120th Street, Los Angeles, California 90059, United States. kewu@cdrewu.edu
Key Words	Diabetic cardiomyopathy; Liraglutide; Glucagon-like peptide-1 receptor; Cardiomyocyte; Endothelial cells; Cell-type specificity
Core Tip	The cellular targets mediating the cardioprotective effects of liraglutide in diabetic cardiomyopathy remain incompletely defined. While recent studies report beneficial cardiac phenotypes, the attribution of these effects to direct cardiomyocyte receptor signaling is not yet conclusively established. This correspondence highlights uncertainties related to cell-type specificity and potential non-myocyte contributions, and emphasizes the need for rigorous cell-type resolved validation. Clarifying the cellular basis of liraglutide action is critical for accurate mechanistic interpretation and future translational applications.
Citation	Su K, Cao PY, Chen G, Wu K. Is the cellular attribution of liraglutide action in diabetic cardiomyopathy conclusive? World J Diabetes 2026; In press

Received	2025-12-03 00:53
Peer-Review Started	2025-12-03 08:45
First Decision by Editorial Office Director	2026-01-08 05:32
Return for Revision	2026-01-08 05:32
Revised	2026-01-16 04:05
Publication Fee Transferred
Second Decision by Editor	2026-01-27 02:37
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-01-27 06:51
Articles in Press	2026-01-27 06:51
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9358 (online)
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