Publication Name	World Journal of Orthopedics
Manuscript ID	117533
Country	China

Category	Surgery
Manuscript Type	Case Report
Article Title	Customized three-dimensional printed titanium ribs combined with bilateral flaps for reconstruction of chest wall defect: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Xian-An Li, Jia-Yi Chen, Jie Bu and Hong-Wei Wu
Funding Agency and Grant Number	Funding Agency Grant Number Hunan Provincial Health and Family Planning Commission C20180690
Corresponding Author	Hong-Wei Wu, Chief Physician, MD, PhD, Principal Investigator, Researcher, Department of Orthopedics, Zhejiang University School of Medicine, The Fourth Affiated Hospital, No. 1 Shangcheng Ave, Yiwu 320002, Zhejiang Province, China. hongweiwu@zju.edu.cn
Key Words	Myxofibrosarcoma; Thoracic wall defect; Three-dimensional printing; Dual free flap; Surgical reconstruction; Case report
Core Tip	This case report details the management of a massive thoracoabdominal wall soft tissue sarcoma using a multidisciplinary, collaborative approach combined with medicine-engineering integration. Following meticulous perioperative optimization, three-dimensional printed titanium alloy prostheses and free bilateral anterolateral thigh myocutaneous flaps were used to reconstruct the extensive bony and soft tissue defects of the chest wall, respectively, with highly satisfactory short-term postoperative outcomes. Notably, the combined thoracoabdominal wall defect at the surgical site measured 750 cm2, which, to the best of our knowledge, represents the largest reported repair of a thoracoabdominal wall defect secondary to soft tissue sarcoma to date.
Citation	Li XA, Chen JY, Bu J, Wu HW. Customized three-dimensional printed titanium ribs combined with bilateral flaps for reconstruction of chest wall defect: A case report. World J Orthop 2026; In press

Received	2025-12-10 01:56
Peer-Review Started	2025-12-10 01:56
First Decision by Editorial Office Director	2026-01-16 06:29
Return for Revision	2026-01-16 06:29
Revised	2026-01-25 08:39
Publication Fee Transferred	2026-01-27 06:58
Second Decision by Editor	2026-02-28 02:30
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-02-28 07:55
Articles in Press	2026-02-28 07:55
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2218-5836 (online)
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