Publication Name	World Journal of Psychiatry
Manuscript ID	117803
Country	China

Category	Medicine, Research & Experimental
Manuscript Type	Clinical Trials Study
Article Title	Congqi Shoushen Tuina Method for generalized anxiety disorder: Clinical outcomes and serum metabolomic profiles
Manuscript Source	Unsolicited Manuscript
All Author List	Jing Zhang, Wei-Biao Li, Xue-Xia Wang, Ting-Ting Han, Sheng Dong, Ya-Nan Sang, Min Lu and Xian-Hui Guo
Funding Agency and Grant Number	Funding Agency Grant Number Henan Province “Double First-class” Establishment Discipline of Chinese Medical Science Research Project HSRP-DFCTCM-2023-1-09 Henan Provincial Key Science and Technology Research Project 252102310469
Corresponding Author	Xian-Hui Guo, PhD, Professor, College of Acupuncture and Massage, Henan University of Chinese Medicine, No. 156 Jinshui East Road, Zhengzhou 450000, Henan Province, China. gxhhactcm@126.com
Key Words	Generalized anxiety disorder; Metabolic dysregulation; Non-targeted metabolomics; Tuina; Congqi Shoushen Tuina Method
Core Tip	The Congqi Shoushen Tuina Method, a distinguished traditional Chinese medicine-specific manipulation therapy, is characterized by its core principles of treating the head and abdomen in tandem and coordinating qi dynamics and mental state synergistically. Mechanistically, it exerts systemic regulatory functions by modulating patients’ serum metabolomic signatures, resulting in a marked amelioration of anxious emotions and associated complications, including sleep disturbances. Given its superior safety, good tolerability, and high patient compliance, this therapeutic approach holds substantial promise for broad clinical translation and application.
Citation	Zhang J, Li WB, Wang XX, Han TT, Dong S, Sang YN, Lu M, Guo XH. Congqi Shoushen Tuina Method for generalized anxiety disorder: Clinical outcomes and serum metabolomic profiles. World J Psychiatry 2026; In press

Received	2025-12-16 01:55
Peer-Review Started	2025-12-16 01:56
First Decision by Editorial Office Director	2026-01-14 08:30
Return for Revision	2026-01-14 08:30
Revised	2026-01-27 05:11
Publication Fee Transferred	2026-01-29 05:19
Second Decision by Editor	2026-02-28 02:30
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-02-28 03:57
Articles in Press	2026-02-28 03:57
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3206 (online)
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