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Publication Name World Journal of Hepatology
Manuscript ID 117996
Country Australia
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Comparing validated hepatocellular carcinoma risk scores for chronic hepatitis B against current Australian surveillance guidelines
Manuscript Source Unsolicited Manuscript
All Author List Ibrahim Mian, Deloshaan Subhaharan, Adam Haig, Rupert Cox, Tariq Masood, Alicia Braund and Natalie Funakoshi
Funding Agency and Grant Number
Corresponding Author Ibrahim Mian, Department of Digestive Health, Gold Coast University Hospital, 1 Hospital Boulevard, Southport, Gold Coast 4215, Queensland, Australia. ibrahim.mian@health.qld.gov.au
Key Words Chronic hepatitis B; Hepatocellular carcinoma surveillance; Risk prediction models; Australian population; Risk Estimation for Hepatocellular Carcinoma in Chronic Hepatitis B; Platelet Age Gender-Hepatitis B; Modified Risk Estimation for hepatocellular carcinoma in chronic hepatitis B
Core Tip Hepatocellular carcinoma (HCC) surveillance in people with chronic hepatitis B (CHB) aims to detect cancer early, however there is a risk of over- or under-surveillance. In this Australian cohort, the validated HCC risk scores Risk Estimation for HCC in CHB, modified Risk Estimation for Hepatocellular Carcinoma in Chronic Hepatitis B, and Platelet Age Gender-Hepatitis B identified substantially fewer patients for surveillance compared with the current Gastroenterological Society of Australia guidelines. Importantly, these risk scores failed to identify all patients who developed HCC, highlighting the limitations of applying population-specific tools to Australia’s heterogeneous CHB population.
Citation Mian I, Subhaharan D, Haig A, Cox R, Masood T, Braund A, Funakoshi N. Comparing validated hepatocellular carcinoma risk scores for chronic hepatitis B against current Australian surveillance guidelines. World J Hepatol 2026; In press
Received
2026-01-04 08:44
Peer-Review Started
2026-01-04 08:44
First Decision by Editorial Office Director
2026-01-19 08:57
Return for Revision
2026-01-21 09:22
Revised
2026-02-18 03:10
Publication Fee Transferred
2026-02-23 00:49
Second Decision by Editor
2026-05-12 02:44
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-05-12 08:11
Articles in Press
2026-05-12 08:11
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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