Publication Name	World Journal of Clinical Cases
Manuscript ID	118087
Country	United States

Category	Oncology
Manuscript Type	Systematic Reviews
Article Title	Direct oral anticoagulants vs low-molecular-weight heparins for cancer-associated thromboembolism
Manuscript Source	Invited Manuscript
All Author List	Faseeh Haider, Faizan Ahmed, Yusra Junaid, Maliha Khalid, Areej Dar, Muhammad Arham, Aman Ullah, Saba Aliha, Muhammad Usman Arshad, Khadija Naeem, Muhammad Moseeb Ali Hashim, Najam Gohar, Asha Ricciuti, Vipul Bhanderi, Fawaz Alenezi and Brijesh Patel
Funding Agency and Grant Number
Corresponding Author	Faseeh Haider, Researcher, Department of Internal Medicine, Allama Iqbal Medical College, Allama Shabbir Ahmed Usmani Road, Lahore 54550, Punjab, Pakistan. faseehhaidermd@gmail.com
Key Words	Cancer-associated thrombosis; Direct oral anticoagulants; Low molecular weight heparins; Meta-regression; Factor Xa inhibitors; Neoplasms
Core Tip	Cancer-associated thrombosis continues to be a major cause of morbidity and mortality in oncology patients, necessitating the selection of anticoagulation medication. This study examined the efficacy and safety of direct oral anticoagulants vs low-molecular-weight heparins. Direct oral anticoagulants showed comparable protection against venous thromboembolism and severe bleeding, with apixaban demonstrating a significant reduction in venous thromboembolism recurrence. Metastasis and platelet count were found as major moderators of bleeding and mortality outcomes in study, indicating the need for personalized anticoagulation methods in cancer treatment.
Citation	Haider F, Ahmed F, Junaid Y, Khalid M, Dar A, Arham M, Ullah A, Aliha S, Arshad MU, Naeem K, Hashim MMA, Gohar N, Ricciuti A, Bhanderi V, Alenezi F, Patel B. Direct oral anticoagulants vs low-molecular-weight heparins for cancer-associated thromboembolism. World J Clin Cases 2026; In press

Received	2025-12-23 08:35
Peer-Review Started	2025-12-23 08:35
First Decision by Editorial Office Director	2026-02-25 07:54
Return for Revision	2026-02-25 07:54
Revised	2026-03-11 22:05
Publication Fee Transferred
Second Decision by Editor	2026-05-12 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-05-12 06:07
Articles in Press	2026-05-12 06:07
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2307-8960 (online)
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