Publication Name	World Journal of Gastroenterology
Manuscript ID	118142
Country	China

Category	Medicine, General & Internal
Manuscript Type	Retrospective Cohort Study
Article Title	Development and validation of a nomogram predicting rebleeding in cirrhotic patients with patent transjugular intrahepatic portosystemic shunt
Manuscript Source	Unsolicited Manuscript
All Author List	Yang-Tian Ren, Jun-Yi Wen, Jing-Jing Tu, Han Zhang, Chuan-Fu Ding, Jiang-Qiang Xiao and Yu-Zheng Zhuge
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China No. 82100652 Nanjing Drum Hospital Youth Development Program No. 2024-LCYJ-PY-27
Corresponding Author	Yu-Zheng Zhuge, PhD, Professor, Department of Gastroenterology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, No. 321 Zhongshan Road, Nanjing 210000, Jiangsu Province, China. yuzheng9111963@aliyun.com
Key Words	Transjugular intrahepatic portosystemic shunt; Oesophagogastric variceal rebleeding; Nomogram; Predictive model; Portal hypertension; Stent patency; Propensity score matching
Core Tip	Rebleeding following technically patent transjugular intrahepatic portosystemic shunt (TIPS) placement remains a significant clinical challenge, especially with the use of reduced-diameter stents aimed at mitigating overt hepatic encephalopathy. Although smaller stents decrease procedure-related complications, they may increase the risk of insufficient shunt flow and subsequent variceal rebleeding. This study identified patients experiencing rebleeding despite shunt patency and evaluated pre-procedural factors associated with this adverse outcome. By establishing a predictive nomogram, this research provides a practical tool for screening high-risk individuals, ultimately supporting individualized clinical decision-making and the selection of optimal TIPS diameters for cirrhotic patients.
Citation	Ren YT, Wen JY, Tu JJ, Zhang H, Ding CF, Xiao JQ, Zhuge YZ. Development and validation of a nomogram predicting rebleeding in cirrhotic patients with patent transjugular intrahepatic portosystemic shunt. World J Gastroenterol 2026; In press

Received	2025-12-25 03:22
Peer-Review Started	2025-12-25 03:22
First Decision by Editorial Office Director	2026-02-25 08:38
Return for Revision	2026-02-25 08:38
Revised	2026-02-28 03:23
Publication Fee Transferred	2026-03-02 05:58
Second Decision by Editor	2026-03-12 02:36
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-03-12 09:33
Articles in Press	2026-03-12 09:33
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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