Publication Name	World Journal of Psychiatry
Manuscript ID	118148
Country	China

Category	Clinical Neurology
Manuscript Type	Observational Study
Article Title	Serum adiponectin and cognitive function in Alzheimer’s disease with comorbid depression
Manuscript Source	Unsolicited Manuscript
All Author List	Chong Song, Wei Zhan, Jia-Yu Tang, Zhu-Hui Liu and Yong-Pan Huang
Funding Agency and Grant Number	Funding Agency Grant Number Education Department of Hunan Province 25C1704 Natural Science Foundation of Hunan Province 2023JJ60263
Corresponding Author	Yong-Pan Huang, Dean, School of Medicine, Changsha Social Work College, No. 22 Xiangzhang Road, Yuhua District, Changsha 410004, Hunan Province, China. songchong0731@163.com
Key Words	Alzheimer’s disease; Depression; Adiponectin; Cognitive function; Correlation
Core Tip	This study demonstrates a significant reduction in serum adiponectin (APN) levels in patients with Alzheimer’s disease (AD) complicated by depression, which progressively declines with worsening disease severity and independently correlates with cognitive impairment. These findings highlight APN as a promising peripheral biomarker for cognitive assessment in AD-depression comorbidity, offering potential pathways for novel therapeutic strategies and more precise clinical monitoring.
Citation	Song C, Zhan W, Tang JY, Liu ZH, Huang YP. Serum adiponectin and cognitive function in Alzheimer’s disease with comorbid depression. World J Psychiatry 2026; In press

Received	2026-01-27 09:59
Peer-Review Started	2026-01-27 09:59
First Decision by Editorial Office Director	2026-02-09 09:16
Return for Revision	2026-02-09 09:16
Revised	2026-02-12 05:50
Publication Fee Transferred	2026-02-14 08:39
Second Decision by Editor	2026-03-20 02:43
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-03-20 06:36
Articles in Press	2026-03-20 06:36
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3206 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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