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Publication Name World Journal of Transplantation
Manuscript ID 118169
Country China
Category Endocrinology & Metabolism
Manuscript Type Minireviews
Article Title Vagal nerve innervation divergence in liver/pancreas: A forgotten key to endocrine recovery after transplantation?
Manuscript Source Invited Manuscript
All Author List Ao-Yun Zhang, Zi-Han Guo, Yuan Huang, Yu-Rou Shi, Xiao Song, Shuai-Yan Wang, Guan-Hu Yang, Yun Liu and Tian-Cheng Xu
Funding Agency and Grant Number
Funding Agency Grant Number
The National Natural Science Foundation, Youth Science Fund Project No. 82305376
The Youth Talent Support Project of the China Acupuncture and Moxibustion Association No. 2024-2026ZGZJXH-QNRC005
The 2024 Jiangsu Province Youth Science and Technology Talent Support Project No. JSTJ-2024-380
Talent Cultivation Program for Young Researchers, Key Laboratory of the Ministry of Education Project No. Zyqt202501 and No. Zyqt202503
Corresponding Author Tian-Cheng Xu, Key Laboratory of Acupuncture and Medicine Research of Ministry of Education, Nanjing University of Chinese Medicine, No. 138 Xianlin Avenue, Qixia District, Nanjing 210023, Jiangsu Province, China. xtc@njucm.edu.cn
Key Words Vagal nerve; Liver/pancreas; Transplantation; Endocrine homeostasis; Organ-specific innervation; Neuromodulation
Core Tip The differences in vagal innervation between the liver and pancreas play an important role in the recovery of endocrine function after transplantation. Cutting-edge strategies such as intraoperative vagus nerve preservation techniques, targeted neuromodulation, and stem cell-derived neurotrophic factor delivery have shown new prospects for improving endocrine dysfunction after transplantation. Future research should focus on the organ-specific mechanisms of vagal innervation, and the development of novel neuromodulatory therapies is of great significance for transplant recipients.
Citation Zhang AY Guo ZH, Huang Y, Shi YR, Song X, Wang SY, Yang GH, Liu Y, Xu TC. Vagal nerve innervation divergence in liver/pancreas: A forgotten key to endocrine recovery after transplantation? World J Transplant 2026; In press
Received
2025-12-26 01:36
Peer-Review Started
2025-12-26 07:36
First Decision by Editorial Office Director
2026-01-12 09:13
Return for Revision
2026-01-12 09:13
Revised
2026-01-18 13:33
Publication Fee Transferred
Second Decision by Editor
2026-02-14 02:35
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-14 09:20
Articles in Press
2026-02-14 09:20
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2220-3230 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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