Publication Name	World Journal of Gastrointestinal Endoscopy
Manuscript ID	118261
Country	Germany

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Cohort Study
Article Title	Moderate sedation with midazolam and propofol is as safe as propofol monotherapy for colonoscopy, but more cost-effective
Manuscript Source	Unsolicited Manuscript
All Author List	Claudia Ott, Philipp Dobsch, Markus Sander, Elisabeth Schnoy and Michael T Pawlik
Funding Agency and Grant Number
Corresponding Author	Claudia Ott, MD, PhD, Internal Medicine and Gastroenterology, Gastroenterology at FAZ, Hildegard-von-Bingen-Str. 1, Regensburg 93053, Bavaria, Germany. claudiaott4@t-online.de
Key Words	Midazolam; Propofol; Preventive colonoscopy; Safety; Costs
Core Tip	Various guideline recommendations for sedation in gastroenterological endoscopy exist, but there is little data available on the use of combination therapy with low-dose midazolam in combination with propofol vs propofol monotherapy (PMT) for short-term outpatient procedures in patients with a low examination risk. This cohort study analysed the safety and costs of a combination therapy with low-dose midazolam in combination with propofol vs PMT in 120 patients undergoing preventive colonoscopy. Combination therapy was as safe as PMT, but was less expensive.
Citation	Ott C, Dobsch P, Sander M, Schnoy E, Pawlik MT. Moderate sedation with midazolam and propofol is as safe as propofol monotherapy for colonoscopy, but more cost-effective. World J Gastrointest Endosc 2026; In press

Received	2025-12-29 06:58
Peer-Review Started	2025-12-29 06:59
First Decision by Editorial Office Director	2026-01-21 08:58
Return for Revision	2026-01-21 08:58
Revised	2026-02-05 11:47
Publication Fee Transferred	2026-02-09 07:04
Second Decision by Editor	2026-03-13 02:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-03-13 08:59
Articles in Press	2026-03-13 08:59
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5190 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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