Publication Name	World Journal of Orthopedics
Manuscript ID	118397
Country	Italy

Category	Orthopedics
Manuscript Type	Minireviews
Article Title	Innovations and future research directions on hip preservation management options for osteonecrosis of the femoral head
Manuscript Source	Invited Manuscript
All Author List	Valerio Pace, Francesco Pezone, Eduardo De Larrea and Pierluigi Antinolfi
Funding Agency and Grant Number
Corresponding Author	Valerio Pace, Department of Trauma and Orthopaedics, “Media Valle del Tevere - Pantalla” Hospital, Via del Buda, Pantalla-Todi 06059, Italy. valeriopace@doctors.org.uk
Key Words	Hip preservation; Avascular necrosis; Femoral head necrosis; Hip replacement; Hip preservation surgery; Femoral head avascular necrosis; Hip osteoarthritis
Core Tip	The past decade has brought substantial advances in hip preservation for Osteonecrosis of the femoral head, particularly through biologically augmented core decompression and innovative implants. Yet high-quality randomized evidence remains sparse, especially for comparative effectiveness across strategies and for long term survivorship. There is an urgent need for multicenter, stage stratified trials with standardized outcome measures to refine algorithms that truly balance joint preservation against timely total hip arthroplasty.
Citation	Pace V, Pezone F, De Larrea E, Antinolfi P. Innovations and future research directions on hip preservation management options for osteonecrosis of the femoral head. World J Orthop 2026; In press

Received	2025-12-31 01:14
Peer-Review Started	2025-12-31 01:14
First Decision by Editorial Office Director	2026-01-20 08:21
Return for Revision	2026-01-20 08:21
Revised	2026-02-21 07:38
Publication Fee Transferred
Second Decision by Editor	2026-05-15 02:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-05-15 08:29
Articles in Press	2026-05-15 08:29
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2218-5836 (online)
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