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Publication Name World Journal of Gastrointestinal Endoscopy
Manuscript ID 118485
Country China
Category Gastroenterology & Hepatology
Manuscript Type Case Report
Article Title Immunoglobulin G4-related sclerosing cholangitis: A case report
Manuscript Source Unsolicited Manuscript
All Author List Yu Xia, Jun-Da Zhu, Tong Su, Lei Shi, Shu-Lei Zhao, Hong-Wei Xu and Chang-Qin Xu
Funding Agency and Grant Number
Funding Agency Grant Number
Young Elite Sponsorship Program of Shandong Provincial Medical Association No. 2024-GJ-0131
Corresponding Author Chang-Qin Xu, Department of Gastroenterology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jingwu Weiqi Road, Jinan 250000, Shandong Province, China. 64791275@qq.com
Key Words Immunoglobulin G4-related sclerosing cholangitis; Isolated Immunoglobulin G4-related sclerosing cholangitis; Autoimmune pancreatitis; Primary sclerosing cholangitis; Case report
Core Tip Immunoglobulin G4-related sclerosing cholangitis (IgG4-SC) is a relatively rare autoimmune disease that typically presents with bile duct stenosis and cholestasis. It is frequently associated with autoimmune pancreatitis; however, a small subset of patients develop IgG4-SC without any extra-biliary involvement from IgG4-related disease. This form, known as isolated IgG4-SC, is particularly challenging to diagnose. This report describes a case of isolated IgG4-SC and suggests that clinicians begin considering this condition in patients who present with unexplained biliary strictures and cholestasis, especially when serum IgG4 levels are elevated.
Citation Xia Y, Zhu JD, Su T, Shi L, SZhao SL, Xu HW, Xu CQ. Immunoglobulin G4-related sclerosing cholangitis: A case report. World J Gastrointest Endosc 2026; In press
Received
2026-01-04 08:34
Peer-Review Started
2026-01-04 08:36
First Decision by Editorial Office Director
2026-01-15 09:00
Return for Revision
2026-01-17 08:49
Revised
2026-01-29 08:50
Publication Fee Transferred
2026-02-01 08:34
Second Decision by Editor
2026-03-13 02:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-03-13 10:15
Articles in Press
2026-03-13 10:15
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-5190 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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