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Publication Name World Journal of Hepatology
Manuscript ID 118615
Country Malaysia
Category Gastroenterology & Hepatology
Manuscript Type Letter to the Editor
Article Title Microplastics as promoters of metabolic dysfunction-associated steatotic liver disease: Mechanistic insights and implications
Manuscript Source Unsolicited Manuscript
All Author List Nabil Eid
Funding Agency and Grant Number
Corresponding Author Nabil Eid, Associate Professor, MD, PhD, Division of Anatomy, Department of Human Biology, School of Medicine, IMU University, Bukit Jalil, Kuala Lumpur 57000, Malaysia. nabilsaleheid@imu.edu.my
Key Words Metabolic dysfunction-associated steatotic liver disease; Non-alcoholic fatty liver disease; Steatosis; Autophagy; Lipophagy, Cytokines; Microplastics; Nanoplastics; Lysosome
Core Tip Metabolic dysfunction-associated steatotic liver disease is the most prevalent chronic liver disease worldwide and carries a risk of progression to hepatocellular carcinoma. Microplastics have emerged as environmental hazards and have been detected in human tissues, including the liver, brain, and blood. Recent preclinical evidence links microplastic exposure to metabolic dysfunction-associated steatotic liver disease through mechanisms involving metabolic stress, inflammation, and autophagy dysfunction, with potential clinical implications.
Citation Eid N. Microplastics as promoters of metabolic dysfunction-associated steatotic liver disease: Mechanistic insights and implications. World J Hepatol 2026; In press
Received
2026-01-07 06:37
Peer-Review Started
2026-01-07 06:38
First Decision by Editorial Office Director
2026-01-27 07:52
Return for Revision
2026-01-27 07:52
Revised
2026-01-28 07:37
Publication Fee Transferred
Second Decision by Editor
2026-03-06 02:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-03-06 08:38
Articles in Press
2026-03-06 08:38
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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