Publication Name	World Journal of Hepatology
Manuscript ID	118804
Country	Japan

Category	Medicine, General & Internal
Manuscript Type	Opinion Review
Article Title	Rethinking noninvasive steatosis indices: Structural limitations and misclassification across the body mass index spectrum
Manuscript Source	Invited Manuscript
All Author List	Kengo Moriyama
Funding Agency and Grant Number
Corresponding Author	Kengo Moriyama, MD, PhD, Professor, Department of Clinical Health Science, Tokai University School of Medicine, 1838 Ishikawa-Machi, Hachioji 192-0032, Tokyo, Japan. kengomoriyama@tokai.ac.jp
Key Words	Metabolic dysfunction-associated steatotic liver disease; Fatty liver index; Hepatic steatosis index; Nonalcoholic fatty liver disease liver fat score; Body mass index; Misclassification; Noninvasive indices; Hepatic steatosis
Core Tip	While noninvasive steatosis markers are widely used, their diagnostic accuracy varies across the body mass index spectrum. Their reliance on anthropometric parameters leads to systematic errors, resulting in overestimation of steatosis and underestimation in lean individuals. Consequently, these tools should be utilized in a context-dependent manner, interpreted alongside imaging and metabolic assessments.
Citation	Moriyama K. Rethinking noninvasive steatosis indices: Structural limitations and misclassification across the body mass index spectrum. World J Hepatol 2026; In press

Received	2026-01-12 01:54
Peer-Review Started	2026-01-12 01:54
First Decision by Editorial Office Director	2026-01-23 09:16
Return for Revision	2026-01-23 09:16
Revised	2026-02-04 07:06
Publication Fee Transferred
Second Decision by Editor	2026-04-16 02:35
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-04-16 09:58
Articles in Press	2026-04-16 09:58
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5182 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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