Publication Name	World Journal of Gastroenterology
Manuscript ID	119071
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Baseline multimodal clinical-radiomics-pathomics model predicts mucosal healing in Crohn’s disease after infliximab therapy
Manuscript Source	Unsolicited Manuscript
All Author List	Han Zhang, Hui-Min Liu, Jia-Xin Pei, Jing Hu, Chao Zhu, Kai-Cai Liu, Chang Rong, Xiao-Min Zheng, Yi Shen, Yong-Ping Cai and Xing-Wang Wu
Funding Agency and Grant Number	Funding Agency Grant Number Research Fund of Anhui Institute of Translational Medicine No. 2023zhyx-C35 Natural Science Foundation of Anhui Province, China No. 2308085MH241
Corresponding Author	Xing-Wang Wu, Department of Radiology, The First Affiliated Hospital of Anhui Medical University, Intersection of Tianhai Road and Feicui Road, Feixi County, Hefei 230022, Anhui Province, China. wuxingwang@ahmu.edu.cn
Key Words	Crohn disease; Mucosal healing; Radiomics; Pathomics; Infliximab
Core Tip	In response to the clinical requirement for an accurate, noninvasive predictive instrument for mucosal healing (MH) in Crohn’s disease (CD), this research endeavors to develop and validate a multimodal integrated model. The combined radiomics-pathomics model forecasts MH in ileal/ileocolonic CD, with area under the curve values of 0.915/0.922, surpassing those of other models. It offers a noninvasive, precise means for predicting MH in CD patients, thereby promoting personalized clinical decision-making and enhancing patient prognoses.
Citation	Zhang H, Liu HM, Pei JX, Hu J, Zhu C, Liu KC, Rong C, Zheng XM, Shen Y, Cai YP, Wu XW. Baseline multimodal clinical-radiomics-pathomics model predicts mucosal healing in Crohn’s disease after infliximab therapy. World J Gastroenterol 2026; In press

Received	2026-01-19 06:34
Peer-Review Started	2026-01-19 06:35
First Decision by Editorial Office Director	2026-02-10 10:51
Return for Revision	2026-02-10 10:51
Revised	2026-02-21 16:24
Publication Fee Transferred	2026-02-23 03:43
Second Decision by Editor	2026-03-17 03:05
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-03-17 07:46
Articles in Press	2026-03-17 07:46
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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