Publication Name	World Journal of Gastroenterology
Manuscript ID	119116
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Opinion Review
Article Title	Reconsidering the role of metabolic dysfunction-associated steatotic liver disease in pancreatic cancer progression
Manuscript Source	Invited Manuscript
All Author List	Yan-Ling Li, Dong-Jie Zhang, Ying-Ying Zhu, Chun-Xi Wang and Qing Liu
Funding Agency and Grant Number
Corresponding Author	Chun-Xi Wang, Department of Gastrointestinal Surgery, The First Hospital of Jilin University, Xinmin Street, Changchun 130000, Jilin Province, China. wangchunxi_2020@126.com
Key Words	Pancreatic cancer; Liver metastasis; Metabolic dysfunction-associated steatotic liver disease; Tumor microenvironment; Prognosis
Core Tip	Metabolic dysfunction-associated steatotic liver disease is biologically linked to hepatic inflammation and immune modulation, yet emerging real-world evidence indicates that it is not an independent determinant of liver metastasis or survival in pancreatic cancer. Clinically, metabolic dysfunction-associated steatotic liver disease should be interpreted as a contextual metabolic comorbidity rather than a decisive prognostic factor, avoiding overinterpretation of incidental hepatic steatosis in risk assessment.
Citation	Li YL, Zhang DJ, Zhu YY, Wang CX, Liu Q. Reconsidering the role of metabolic dysfunction-associated steatotic liver disease in pancreatic cancer progression. World J Gastroenterol 2026; In press

Received	2026-01-20 01:53
Peer-Review Started	2026-01-20 01:54
First Decision by Editorial Office Director	2026-02-14 07:48
Return for Revision	2026-02-14 07:48
Revised	2026-02-21 14:18
Publication Fee Transferred
Second Decision by Editor	2026-03-19 02:51
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-03-19 09:30
Articles in Press	2026-03-19 09:30
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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