Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	119136
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Comparative analysis of curative efficacy and prognostic factors across treatment modalities for early-stage hepatocellular carcinoma
Manuscript Source	Unsolicited Manuscript
All Author List	Wen Zheng, Ping Lv, Qiang Zhu, Qing-Lin Zhang, Gang-Gang Yin and Wei-Gang Chen
Funding Agency and Grant Number
Corresponding Author	Wei-Gang Chen, MD, Department of Gastroenterology, The First Affiliated Hospital of Shihezi University, No. 107, North 2nd Road, Hongshan Sub-district, Shihezi 832000, Xinjiang Uygur Autonomous Region, China., Shihezi 832000, China. 13579456959@126.com
Key Words	Hepatocellular carcinoma; Overall survival rate; Progression free survival rate; Radiofrequency ablation; Curative resection
Core Tip	Our findings support liver resection (LR) as the first-line preferred treatment modality for hepatocellular carcinoma (HCC) patients with Barcelona Clinic Liver Cancer 0/A stages. Simultaneously, we observed that combination therapy regimens achieve non-inferior overall survival and progression-free survival benefits compared to LR alone. Therefore, treatment-eligible early-stage HCC patients clinically indicated for combination therapy should actively pursue such regimens to attain similarly favorable prognostic outcomes.
Citation	Zheng W, Lv P, Zhu Q, Zhang QL, Yin GG, Chen WG. Comparative analysis of curative efficacy and prognostic factors across treatment modalities for early-stage hepatocellular carcinoma. World J Gastrointest Oncol 2026; In press

Received	2026-01-23 09:59
Peer-Review Started	2026-01-23 09:59
First Decision by Editorial Office Director	2026-02-04 08:19
Return for Revision	2026-02-04 08:19
Revised	2026-02-12 06:18
Publication Fee Transferred	2026-02-14 06:16
Second Decision by Editor	2026-03-03 02:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-03-03 09:37
Articles in Press	2026-03-03 09:37
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
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