Publication Name	World Journal of Clinical Cases
Manuscript ID	119232
Country	Albania

Category	Neurosciences
Manuscript Type	Case Report
Article Title	Late-onset neurological manifestations of X-linked adrenoleukodystrophy in a male with childhood-onset Addison’s disease: A case report
Manuscript Source	Invited Manuscript
All Author List	Pavllo Djamandi, Hajdi Gorica, Olga Kyriakou, Ergys Xhukellari, Arben Rroji and Gentian Vyshka
Funding Agency and Grant Number
Corresponding Author	Gentian Vyshka, Department of Biomedical and Experimental, Faculty of Medicine, University of Medicine, Rr. Dibres 371, Tirana 1005, Albania. gvyshka@gmail.com
Key Words	X-linked adrenoleukodystrophy; Addison-only; Late-onset; Psychiatric symptoms; ABCD1 gene; Case report
Core Tip	Adrenoleukodystrophies are a heterogeneous neurological occurrence and sometimes their differential diagnosis might be difficult. Addison disease among other background conditions might be related to such a progressive disorder that could lead to severe neurological injury. We present a case where the nervous symptomatology was delayed vis-à-vis the initial and main disease, and whose psychiatric signs preceded gait instability, impaired balance, and dysarthria. Imaging and genetic studies are of particular diagnostic importance in this setting.
Citation	Djamandi P, Gorica H, Kyriakou O, Xhukellari E, Rroji A, Vyshka G. Late-onset neurological manifestations of X-linked adrenoleukodystrophy in a male with childhood-onset Addison’s disease: A case report. World J Clin Cases 2026; In press

Received	2026-01-23 02:59
Peer-Review Started	2026-01-23 03:00
First Decision by Editorial Office Director	2026-02-06 10:08
Return for Revision	2026-02-06 10:08
Revised	2026-02-12 18:08
Publication Fee Transferred
Second Decision by Editor	2026-03-03 02:36
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-03-03 07:51
Articles in Press	2026-03-03 07:51
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2307-8960 (online)
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