Publication Name	World Journal of Clinical Oncology
Manuscript ID	119365
Country	China

Category	Respiratory System
Manuscript Type	Observational Study
Article Title	Construction and validation of a multiparameter diagnostic model based on conventional tumor markers and cytokines for lung cancer
Manuscript Source	Unsolicited Manuscript
All Author List	Yi-Ning Zhang, Tao Jiang, Peng-Jun Zhang and Hui-Juan Wang
Funding Agency and Grant Number	Funding Agency Grant Number the National Key Research and Development Program of China 2020YFC2004604
Corresponding Author	Hui-Juan Wang, MD, Department of Respiratory and Critical Care Medicine, Beijing Chao-Yang Hospital, Beijing Institute of Respiratory Medicine, Capital Medical University, Gongti South Road NO.8 Beijing China, Beijing 100020, China. 13466791738@163.com
Key Words	Lung cancer; Tumor markers; Cytokines; Binary logistic regression; Detection; Carcinoembryonic antigen
Core Tip	We aimed to evaluate the diagnostic value of conventional tumor markers and cytokines and construct a multiparameter diagnostic model. After four multiparameter joint analysis methods analysis, a model that included carcinoembryonic antigen, cytokeratin 19 fragment, interleukin-8 and tumor necrosis factor-alpha for the detection of lung cancer was built and validated. It may provide more comprehensive theoretical support for the diagnosis and targeted therapy of lung cancer.
Citation	Zhang YN, Jiang T, Zhang PJ, Wang HJ. Construction and validation of a multiparameter diagnostic model based on conventional tumor markers and cytokines for lung cancer. World J Clin Oncol 2026; In press

Received	2026-01-30 09:41
Peer-Review Started	2026-01-30 09:41
First Decision by Editorial Office Director	2026-02-09 09:25
Return for Revision	2026-02-09 09:25
Revised	2026-02-10 12:00
Publication Fee Transferred	2026-02-11 07:05
Second Decision by Editor	2026-03-06 02:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-03-06 06:29
Articles in Press	2026-03-06 06:29
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2218-4333 (online)
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