Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	119504
Country	South Korea

Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Optimizing radiofrequency ablation parameters for perianal fistula treatment: A porcine model study
Manuscript Source	Unsolicited Manuscript
All Author List	Sunseok Yoon, Woong Bae Ji, Jun Won Um and Kwang Dae Hong
Funding Agency and Grant Number	Funding Agency Grant Number Korea University Ansan Hospital O2310671 Seoul R&BD Program BT250226 RF Medical Co., Ltd., Seoul, Republic of Korea
Corresponding Author	Kwang Dae Hong, MD, PhD, Professor, Colorectal Surgery, Korea University Ansan Hospital, 123 Joekgum-ro, Danwon-gu, Ansan 15355, South Korea. drhkd@korea.ac.kr
Key Words	Fistula; Perianal fistula; Radiofrequency ablation; Swine; Thermal therapy
Core Tip	Endoluminal radiofrequency ablation (RFA) is a sphincter-preserving option for perianal fistulas. However, standardized energy settings validated in true fistula tissue are lacking. Using a porcine model of perianal fistula, we performed ex vivo prescreening and in vivo histological validation of four candidate settings with a 50-mm segmental RFA catheter. The 120 °C/24 seconds setting produced the most effective ablation (highest ablation/granulation ratio) with the deepest and most consistent burn depth along the tract, providing a practical reference parameter for further translational studies.
Citation	Yoon S, Ji WB, Um JW, Hong KD. Optimizing radiofrequency ablation parameters for perianal fistula treatment: A porcine model study. World J Gastrointest Surg 2026; In press

Received	2026-01-30 01:34
Peer-Review Started	2026-01-30 01:34
First Decision by Editorial Office Director	2026-02-04 09:52
Return for Revision	2026-02-04 09:52
Revised	2026-02-13 06:54
Publication Fee Transferred	2026-02-20 11:08
Second Decision by Editor	2026-03-13 02:43
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-03-13 05:57
Articles in Press	2026-03-13 05:57
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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