| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Natural history of asymptomatic subepithelial lesions of the upper gastrointestinal tract: A multicenter study in Korea
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yonghoon Choi, Jae Yong Park, Sung Eun Kim, Jae Myung Park, Joon Sung Kim, Hyunsoo Chung, Seung Han Kim, Chan Hyuk Park, Sang Hoon Kim, Seon-Young Park, Bong Eun Lee, Seung Woo Lee, Ayoung Lee, Jeong Hoon Lee, Da Hyun Jung, Hyeong Ho Jo, In Hyuk Yoo, Byung-Hoon Min and Hwoon-Yong Jung |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| The Korean College of Helicobacter and Upper Gastrointestinal Research Foundation Grant |
KCHUGR-202302502 |
|
| Corresponding Author |
Sung Eun Kim, Department of Internal Medicine, Kosin University College of Medicine, 262, Gamcheon-ro, Seo-gu, Busan 49267, South Korea. solefide@hanmail.net |
| Key Words |
Subepithelial lesions; Natural course; Prognosis; Gastrointestinal neoplasms; Subepithelial lesions; Natural course; Prognosis |
| Core Tip |
In this large multicenter cohort of asymptomatic upper gastrointestinal subepithelial lesions (SELs), long-term follow-up demonstrated a low cumulative risk of progression, with a 5-year risk of only 1% for intervention and 8% for significant (≥ 25%) size increase. Younger age, larger baseline size, mucosal erosion, and heterogeneous echogenicity were associated with lesion growth, whereas the rolling sign was protective. These findings support conservative management with less intensive surveillance for SELs < 3 cm without high-risk features. |
| Citation |
Choi Y, Park JY, Kim SE, Park JM, Kim JS, Chung H, Kim SH, Park CH, Kim SH, Park SY, Lee BE, Lee SW, Lee A, Lee JH, Jung DH, Jo HH, Yoo IH, Min BH, Jung HY. Natural history of asymptomatic subepithelial lesions of the upper gastrointestinal tract: A multicenter study in Korea. World J Gastroenterol 2026; In press |
