Publication Name	World Journal of Cardiology
Manuscript ID	119863
Country	United States

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Systematic Reviews
Article Title	Systematic review and meta-analysis of prognostic markers in transthyretin amyloid cardiomyopathy
Manuscript Source	Unsolicited Manuscript
All Author List	Tarun Dalia, Varun Kohli, Amandeep Goyal, Siva Naga Yarrarapu, Harsimar Singh, Joseph Mancuso, Anureet Malhotra, Jennifer Schram, Pankaj Bansal and Zubair Shah
Funding Agency and Grant Number
Corresponding Author	Zubair Shah, Assistant Professor, MD, Department of Cardiovascular Medicine, University of Kansas Medical Center, 3901 Rainbow Boulevard, Kansas, KS 66160, United States. zshah2@kumc.edu
Key Words	Transthyretin amyloid cardiomyopathy; Prognosis; Gillmore staging; Biomarkers; Echocardiogram; Glomerular filtration rate
Core Tip	We conducted systematic review and meta-analysis assessing prognostic tools in transthyretin amyloid cardiomyopathy (ATTR-CM) amyloidosis. Out of 7272 studies identified, 42 studies (13145 patients) were included. Prognostic factors associated with higher odds of mortality in transthyretin cardiomyopathy included: higher Gillmore staging, B type Natriuretic peptide, NT pro-BNP, troponin-T, interventricular septal thickness, New York heart association class. Prognostication of ATTR-CM patients can significantly aid in predicting disease severity and guide timely initiation of appropriate treatment strategies.
Citation	Dalia T, Kohli V, Goyal A, Yarrarapu SN, Singh H, Mancuso J, Malhotra A, Schram J, Bansal P, Shah Z. Systematic review and meta-analysis of prognostic markers in transthyretin amyloid cardiomyopathy. World J Cardiol 2026; In press

Received	2026-02-09 01:39
Peer-Review Started	2026-02-09 01:40
First Decision by Editorial Office Director	2026-02-25 07:56
Return for Revision	2026-02-25 07:56
Revised	2026-03-20 00:43
Publication Fee Transferred	2026-03-23 23:17
Second Decision by Editor	2026-04-16 02:35
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-04-16 08:59
Articles in Press	2026-04-16 08:59
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Typeset the Manuscript

ISSN	1949-8462 (online)
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