Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	119941
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Cohort Study
Article Title	Anti-reflux mucosectomy is associated with better short-term symptoms than double-dose proton pump inhibitor in reflux esophagitis patients
Manuscript Source	Unsolicited Manuscript
All Author List	Wen-Jun Jiang, Jie Liu, Ying-Ling Liu, Meng-Die Tang, Yuan Sheng and Ye-Tao Wang
Funding Agency and Grant Number	Funding Agency Grant Number Scientific Research Plan Project of Universities in Anhui Province No. 2024AH052045
Corresponding Author	Ye-Tao Wang, Chief Physician, Department of Gastroenterology, The First Affiliated Hospital of University of Science and Technology of China (USTC), Division of Life Sciences and Medicine, University of Science and Technology of China, No. 17 Lujiang Road, Hefei 230001, Anhui Province, China. wangyt96@163.com
Key Words	Gastroesophageal reflux disease; Anti-reflux mucosectomy; Quality of life; Reflux esophagitis; Proton pump inhibitor
Core Tip	Anti-reflux mucosectomy (ARMS) is an innovative endoscopic technique developed for the management of refractory gastroesophageal reflux disease. The procedure aims to induce submucosal fibrosis following mucosectomy at the esophagogastric junction, offering the advantage of a minimally invasive endoscopic approach. Since its inception, multiple prospective and retrospective studies have been conducted to evaluate the clinical outcomes associated with ARMS. In this context, we present the findings of a retrospective cohort study comparing the efficacy of ARMS to twice-daily proton pump inhibitor (PPI) therapy in a well-defined population of patients exhibiting moderate-to-severe regurgitation despite once-daily PPI treatment.
Citation	Jiang WJ, Liu J, Liu YL, Tang MD, Sheng Y, Wang YT. Anti-reflux mucosectomy is associated with better short-term symptoms than double-dose proton pump inhibitor in reflux esophagitis patients. World J Gastrointest Surg 2026; In press

Received	2026-02-11 02:36
Peer-Review Started	2026-02-11 02:52
First Decision by Editorial Office Director	2026-03-03 08:57
Return for Revision	2026-03-03 08:57
Revised	2026-03-11 11:19
Publication Fee Transferred	2026-03-12 10:09
Second Decision by Editor	2026-04-03 02:44
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-04-03 05:50
Articles in Press	2026-04-03 05:50
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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