Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	120942
Country	China

Category	Medicine, Research & Experimental
Manuscript Type	Observational Study
Article Title	Quantitative TP53 circulating tumor DNA predicts tumor response and survival outcomes in esophageal squamous cell carcinoma
Manuscript Source	Unsolicited Manuscript
All Author List	Ren-Tong Gu, Tao Liu, Zhi-Sheng Piao, Hai Jin, Xiao-Wei Wang and Xin Li
Funding Agency and Grant Number	Funding Agency Grant Number Science and Technology Commission of Shanghai Municipality, China No. 15411951700
Corresponding Author	Xin Li, Department of Thoracic Surgery, Changhai Hospital, No. 168 Changhai Road, Shanghai 200433, China. 717221600@qq.com
Key Words	Circulating tumor DNA; TP53; Esophageal squamous cell carcinoma; Tumor response; Variant allele frequency
Core Tip	Based on a study of 63 esophageal squamous cell carcinoma patients, quantitative analysis of TP53 circulating tumor DNA may help predict postoperative recurrence, assess response to neoadjuvant chemotherapy, and stratify patient survival, suggesting its potential value as a noninvasive biomarker for longitudinal monitoring.
Citation	Gu RT, Liu T, Piao ZS, Jin H, Wang XW, Li X. Quantitative TP53 circulating tumor DNA predicts tumor response and survival outcomes in esophageal squamous cell carcinoma. World J Gastrointest Oncol 2026; In press

Received	2026-03-12 02:20
Peer-Review Started	2026-03-12 02:21
First Decision by Editorial Office Director	2026-03-26 09:42
Return for Revision	2026-03-26 09:42
Revised	2026-03-30 01:07
Publication Fee Transferred	2026-04-01 02:46
Second Decision by Editor	2026-05-11 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-05-11 09:59
Articles in Press	2026-05-11 09:59
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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