Publication Name	World Journal of Gastroenterology
Manuscript ID	121499
DOI	10.3748/wjg.121499
Country	Russia

Category	Genetics & Heredity
Manuscript Type	Minireviews
Article Title	Modern possibilities of molecular diagnostics contribute to improving the effectiveness of therapy against Helicobacter pylori
Manuscript Source	Unsolicited Manuscript
All Author List	Larisa Alexandrovna Tsapkova, Natalia Alexandrovna Bodunova and Vera Vasilyevna Polyakova
Funding Agency and Grant Number
Corresponding Author	Larisa Alexandrovna Tsapkova, PhD, Senior Researcher, Center for Personalized Medicine, SBIH Moscow Clinical Scientific and Practical Center named after A.S. Loginov of DHM, Novogireevskay 1, Moscow 111123, Russia. tsapkovala@zdrav.mos.ru
Key Words	Helicobacter pylori; Molecular markers; Eradication therapy; Molecular diagnostics; Pharmacogenetics
Core Tip	The timely diagnosis and successful treatment of Helicobacter pylori are critical strategies for preventing stomach cancer. The effectiveness of eradication therapy depends on specific bacterial and host factors, and how well these are considered when selecting a treatment regimen. This review highlights how bacterial and host molecular factors impact the effectiveness of anti-Helicobacter therapy. Currently known molecular predictors of eradication efficacy, genetic markers involved in the metabolism of drugs used to eradicate Helicobacter pylori, and the associated individual risks of side effects are presented.
Citation	Tsapkova LA, Bodunova NA, Polyakova VV. Modern possibilities of molecular diagnostics contribute to improving the effectiveness of therapy against Helicobacter pylori. World J Gastroenterol 2026; In press DOI: https://doi.org/10.3748/wjg.121499
PDF	121499-in-press.pdf

Received	2026-04-02 00:47
Peer-Review Started	2026-04-02 00:59
First Decision by Editorial Office Director	2026-05-14 03:49
Return for Revision	2026-05-14 03:49
Revised	2026-06-16 17:03
Publication Fee Transferred
Second Decision by Editor	2026-11-05 03:30
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-11-05 05:17
Articles in Press	2026-11-05 05:17
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
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