Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	121850
DOI	10.4251/wjgo.121850
Country	China

Category	Oncology
Manuscript Type	Meta-Analysis
Article Title	Prognostic significance of Fusobacterium nucleatum in colorectal cancer using reconstructed survival data
Manuscript Source	Unsolicited Manuscript
All Author List	Yi-Xiao Liu, Zhi-Heng Chen, Guang-Jian Dou, Jia-Jun Lu and Yuan Zhou
Funding Agency and Grant Number	Funding Agency Grant Number National Clinical Key Speciality Construction Project - Oncology No. 2023-GJZK-001 Jiaxing City and Provinces to Build Medical Key Disciplines-Oncology No. 2023-SSGJ-001
Corresponding Author	Yuan Zhou, Associate Professor, MD, Department of Gastrointestinal Surgery, The Affiliated Hospital of Jiaxing University and The First Hospital of Jiaxing, No. 1882 Zhonghuan South Road, Jiaxing 314000, Zhejiang Province, China. zhouyuan0422@zjxu.edu.cn
Key Words	Fusobacterium nucleatum; Colorectal cancer; Prognosis; Survival; Meta-analysis; Individual patient data; Kaplan-Meier curve; Restricted mean survival time
Core Tip	This meta-analysis evaluated the prognostic significance of tissue Fusobacterium nucleatum (F. nucleatum) abundance in colorectal cancer using reconstructed individual patient data from Kaplan-Meier curves. High/positive F. nucleatum expression was associated with poorer disease-free survival and cancer-specific survival, whereas no significant association was observed for overall survival. These findings suggest that F. nucleatum may be more closely associated with recurrence and cancer-specific mortality than with all-cause mortality, although further validation is required.
Citation	Liu YX, Chen ZH, Dou GJ, Lu JJ, Zhou Y. Prognostic significance of Fusobacterium nucleatum in colorectal cancer using reconstructed survival data. World J Gastrointest Oncol 2026; In press DOI: https://doi.org/10.4251/wjgo.121850
PDF	121850-in-press.pdf

Received	2026-04-03 03:21
Peer-Review Started	2026-04-03 03:23
First Decision by Editorial Office Director	2026-04-10 06:04
Return for Revision	2026-04-10 06:04
Revised	2026-06-13 10:24
Publication Fee Transferred	2026-06-28 11:36
Second Decision by Editor	2026-08-18 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-08-18 09:21
Articles in Press	2026-08-18 09:21
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
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