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Publication Name World Journal of Translational Medicine
Manuscript ID 121879
DOI 10.5528/wjtm.121879
Country Greece
Category Respiratory System
Manuscript Type Minireviews
Article Title Antiplatelet therapy in pulmonary embolism: Mechanisms and evidence
Manuscript Source Invited Manuscript
All Author List Tsampika-Vasileia Kalamara, Konstantinos Dodos and Vasiliki E Georgakopoulou
Funding Agency and Grant Number
Corresponding Author Vasiliki E Georgakopoulou, Department of Pathophysiology, Laiko General Hospital, Medical School of National and Kapodistrian University of Athens, 17 Agiou Toma Street, Athens 11527, Greece. vaso_georgakopoulou@hotmail.com
Key Words Pulmonary embolism; Platelets; Platelet aggregation inhibitors; Anticoagulation; Endothelial dysfunction
Core Tip Although pulmonary embolism (PE) is classically considered a fibrin-rich, anticoagulation-responsive disorder, platelets are increasingly recognized as active participants in venous thrombogenesis and thrombo-inflammatory signaling. This mini-review examines the mechanistic and clinical evidence linking platelets to PE and critically evaluates the current and potential role of antiplatelet therapy in its prevention and management.
Citation Kalamara TV, Dodos K, Georgakopoulou VE. Antiplatelet therapy in pulmonary embolism: Mechanisms and evidence. World J Transl Med 2026; In press
PDF 121879-in-press.pdf
Received
2026-04-03 05:41
Peer-Review Started
2026-04-13 00:33
First Decision by Editorial Office Director
2026-05-25 01:46
Return for Revision
2026-05-27 07:21
Revised
2026-07-14 15:52
Publication Fee Transferred
Second Decision by Editor
2026-08-31 03:15
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-08-31 08:10
Articles in Press
2026-08-31 08:10
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2220-6132 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com