Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	123447
DOI	10.4251/wjgo.123447
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Artificial intelligence for endoscopic correlates of Correa’s cascade in gastric precancerous lesions and early neoplasia
Manuscript Source	Invited Manuscript
All Author List	Hon Ho Yu, In Neng Chan, Jin-Hui Wang, Ye-Ying Qin, In Weng Chan and Pak Kin Wong
Funding Agency and Grant Number	Funding Agency Grant Number Science and Technology Development Fund of Macau No. 0026/2022/A
Corresponding Author	Pak Kin Wong, Department of Electromechanical Engineering, University of Macau, Avenida da Universidade, Taipa, Macau 999078, China. fstpkw@um.edu.mo
Key Words	Early gastric cancer; Gastric precancerous conditions; Artificial intelligence; Upper gastrointestinal endoscopy; Correa’s cascade
Core Tip	This article applies Correa’s cascade as a clinical framework for evaluating artificial intelligence (AI) in upper endoscopy. Rather than directly identifying biological progression, current AI systems recognize visible endoscopic phenotypes associated with gastritis, atrophy, intestinal metaplasia, dysplasia, and early gastric cancer. By integrating histopathology, endoscopic appearance, AI task design, reference standards, validation level, and clinical decision impact, this review demonstrates why high image-level accuracy may overestimate clinical utility. Future research should emphasize prospective, multicenter, video-based validation together with patient-level and procedure-level outcome assessment.
Citation	Yu HH, Chan IN, Wang JH, Qin YY, Chan IW, Wong PK. Artificial intelligence for endoscopic correlates of Correa’s cascade in gastric precancerous lesions and early neoplasia. World J Gastrointest Oncol 2026; In press DOI: https://doi.org/10.4251/wjgo.123447
PDF	123447-in-press.pdf

Received	2026-05-19 07:48
Peer-Review Started	2026-05-19 07:48
First Decision by Editorial Office Director
Return for Revision	2026-06-29 05:52
Revised	2026-07-21 10:07
Publication Fee Transferred
Second Decision by Editor	2026-08-12 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-08-14 09:25
Articles in Press	2026-08-14 09:25
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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