Publication Name	World Journal of Gastroenterology
Manuscript ID	123472
DOI	10.3748/wjg.123472
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Novel magnetic tracking-based three-dimensional trajectory small bowel capsule endoscopy system for lesion localization: An in vivo animal study
Manuscript Source	Unsolicited Manuscript
All Author List	Yi-Zhi Chen, Xi Jiang, Chao Xu, Chen He, Xiao-Ou Qiu, Saif Ullah, Qing Song, Zhao-Shen Li and Zhuan Liao
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China No. 82500813 National Natural Science Foundation of China No. 82400777 Shanghai “Pioneer Program” Bio-Hybrid Robot Project No. 25XF3200800 “Ixplora Scholar”-Shanghai Academy of Natural Science
Corresponding Author	Zhuan Liao, Professor, Department of Gastroenterology, Changhai Hospital, Naval Medical University, No. 168 Changhai Road, Shanghai 200433, China. liaozhuan@smmu.edu.cn
Key Words	Capsule endoscopy; Small bowel; Lesion localization; Magnetic tracking; Surgical planning
Core Tip	Small bowel capsule endoscopy (SBCE) is widely used but lacks accurate lesion localization. This study evaluated the feasibility and efficacy of a novel wearable magnetic tracking-based three-dimensional (3D) trajectory SBCE system for lesion localization. Using canine models with surgically placed intestinal simulated lesions, the system achieved 100% lesion detection, generated complete and continuous 3D trajectories, and provided accurate pylorus-to-lesion distance measurements with a mean relative error of 5.03% ± 2.05%. This is the first in vivo animal study to evaluate an SBCE localization system capable of directly measuring pylorus-to-lesion distances, underscoring its potential for clinical translation.
Citation	Chen YZ, Jiang X, Xu C, He C, Qiu XO, Ullah S, Song Q, Li ZS, Liao Z. Novel magnetic tracking-based three-dimensional trajectory small bowel capsule endoscopy system for lesion localization: An in vivo animal study. World J Gastroenterol 2026; In press DOI: https://doi.org/10.3748/wjg.123472
PDF	123472-in-press.pdf

Received	2026-05-27 06:33
Peer-Review Started	2026-05-27 06:34
First Decision by Editorial Office Director
Return for Revision	2026-07-24 02:55
Revised	2026-08-04 17:35
Publication Fee Transferred	2026-08-20 01:45
Second Decision by Editor	2026-11-02 02:19
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-11-04 10:00
Articles in Press	2026-11-04 10:00
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
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