Publication Name	World Journal of Clinical Cases
Manuscript ID	123670
DOI	10.12998/wjcc.123670
Country	South Korea

Category	Orthopedics
Manuscript Type	Case Report
Article Title	Extensive multiple calcinosis cutis in seronegative limited cutaneous scleroderma (CREST variant): A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Hyo Yeol Lee, Sun Kyoung Lee, Hosung Kim and Seo Won Kang
Funding Agency and Grant Number
Corresponding Author	Hyo Yeol Lee, Department of Orthopaedic Surgery, Chungbuk National University Hospital, Chungbuk National University College of Medicine, 776, 1Sunwhan-ro, Seowon-gu, Cheongju 28644, Chungbuk, South Korea. thebonedoctor@hanmail.net
Key Words	Calcinosis cutis; Surgical excision; Scleroderma; Seronegative CREST variant; Case report
Core Tip	This case describes a seronegative CREST variant presenting with widespread calcinosis cutis involving the prepatellar region, both elbows, and trunk, accompanied by Raynaud’s phenomenon and clinically diagnosed sclerodactyly. Surgical excision of the symptomatic lesions provided clinical resolution and enabled histopathological assessment demonstrating chronic lymphocytic inflammation and fibrosis. Negative autoimmune serology alone should not exclude limited cutaneous systemic sclerosis when characteristic clinical manifestations are present.
Citation	Lee HY, Lee SK, Kim H, Kang SW. Extensive multiple calcinosis cutis in seronegative limited cutaneous scleroderma (CREST variant): A case report. World J Clin Cases 2026; In press DOI: https://doi.org/10.12998/wjcc.123670
PDF	123670-in-press.pdf

Received	2026-05-26 06:05
Peer-Review Started	2026-05-26 06:06
First Decision by Editorial Office Director
Return for Revision	2026-07-06 06:12
Revised	2026-07-19 04:51
Publication Fee Transferred	2026-07-29 11:48
Second Decision by Editor	2026-08-27 02:44
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-08-28 09:23
Articles in Press	2026-08-28 09:23
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com