Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	123680
DOI	10.4240/wjgs.123680
Country	China

Category	Surgery
Manuscript Type	Randomized Controlled Trial
Article Title	Analysis of the efficacy and safety of ultrasound-guided transversus abdominis plane block in surgery for children with acute appendicitis
Manuscript Source	Unsolicited Manuscript
All Author List	Xiao-Yan Zhou, Ying Han and Shuo-Xiong Wu
Funding Agency and Grant Number
Corresponding Author	Shuo-Xiong Wu, Chief Physician, Department of Anesthesiology, Affiliated Children’s Hospital of Jiangnan University (Wuxi Children’s Hospital), No. 299 Qingyang Road, Liangxi District, Wuxi 214000, Jiangsu Province, China. shuoxiongwu@163.com
Key Words	Appendicitis; Nerve block; Ultrasound; Pain; Hemodynamics; Postoperative complications
Core Tip	This study examines the clinical application of ultrasound-guided transversus abdominis plane block in pediatric patients undergoing appendectomy for acute appendicitis. By comparing this technique with conventional general anesthesia combined with local infiltration anesthesia, the research systematically evaluates the effects of transversus abdominis plane block on perioperative anesthetic requirements, hemodynamic stability, and stress response levels in children. Additionally, the study comprehensively analyzes its efficacy in postoperative pain management and recovery quality improvement while verifying its clinical safety. The findings aim to provide evidence-based support for optimizing perioperative anesthesia management in pediatric acute appendicitis surgery.
Citation	Zhou XY, Han Y, Wu SX. Analysis of the efficacy and safety of ultrasound-guided transversus abdominis plane block in surgery for children with acute appendicitis. World J Gastrointest Surg 2026; In press DOI: https://doi.org/10.4240/wjgs.123680
PDF	123680-in-press.pdf

Received	2026-06-30 10:26
Peer-Review Started	2026-06-30 10:26
First Decision by Editorial Office Director
Return for Revision	2026-07-27 03:39
Revised	2026-08-05 08:36
Publication Fee Transferred	2026-08-14 05:15
Second Decision by Editor	2026-09-10 02:43
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-09-10 10:07
Articles in Press	2026-09-10 10:07
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com