Publication Name	World Journal of Diabetes
Manuscript ID	123877
DOI	10.4239/wjd.123877
Country	China

Category	Endocrinology & Metabolism
Manuscript Type	Retrospective Study
Article Title	Magnetic resonance imaging-derived bone marrow fat fraction and vertebral fractures in type 2 diabetes and osteoporosis
Manuscript Source	Unsolicited Manuscript
All Author List	Fei-Xiong Wang and Huan-Qing Chen
Funding Agency and Grant Number
Corresponding Author	Huan-Qing Chen, Chief Physician, Department of Orthopedics, Pingyang Hospital of Wenzhou Medical University, No. 555 Kun’ao Avenue, Kunyang Town, Pingyang, Wenzhou 325400, Zhejiang Province, China. chenhuanqing1986@outlook.com
Key Words	Magnetic resonance imaging fat quantification parameters; Type 2 diabetes mellitus; Osteoporosis; Fracture; Nomogram
Core Tip	This study investigated factors associated with prevalent osteoporotic vertebral compression fractures in patients with type 2 diabetes and osteoporosis, focusing specifically on magnetic resonance imaging-derived vertebral marrow fat fraction (FF). Age, fasting blood glucose, 25-hydroxyvitamin D, and T-score were independently associated with prevalent osteoporotic vertebral compression fracture, whereas L2 FF was not. A combined model high discrimination, but adding L2 FF did not significantly improve discrimination. The incremental value of L2 FF remains uncertain.
Citation	Wang FX, Chen HQ. Magnetic resonance imaging-derived bone marrow fat fraction and vertebral fractures in type 2 diabetes and osteoporosis. World J Diabetes 2026; In press DOI: https://doi.org/10.4239/wjd.123877
PDF	123877-in-press.pdf

Received	2026-06-18 10:30
Peer-Review Started	2026-06-23 00:05
First Decision by Editorial Office Director
Return for Revision	2026-08-06 02:23
Revised	2026-09-09 13:03
Publication Fee Transferred
Second Decision by Editor	2026-10-28 00:31
Second Decision by Editor-in-Chief	2026-10-29 00:08
Final Decision by Editorial Office Director	2026-11-05 07:32
Articles in Press	2026-11-05 07:32
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9358 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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