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Articles in Press
11/4/2026 10:20:29 AM | Browse: 5 | Download: 1
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Basic Study |
| Article Title |
Long intergenic non-protein coding RNA 00657/miR-218-2-3p/cyclin D1 axis drives gastric cancer chemoresistance
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Quan-Xing Liao, Tian Wang, Jin-Fu He, Chang Liu, Gang-Qiang Wang, Qing-Jun He, Jin Wang, Li-Si Zeng and Run-Ya Fang |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| High-Tech and New Technology Project of Guangdong Province |
No. 10110207100204 |
| Guangzhou Science and Technology Program |
No. 2025A03J3683 |
| Talent Cultivation Program of Affiliated Cancer Hospital of Guangzhou Medical University |
No. FY202401 |
| Weiji Health and Medical Development Foundation of Guangdong Province |
No. K-202104-4 |
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| Corresponding Author |
Run-Ya Fang, Chief Physician, Department of General Surgery, Guangzhou Institution of Cancer Research and The Affiliated Cancer Hospital, Guangzhou Medical University, No. 78 Hengzhigang Road, Dengfeng Subdistrict, Yuexiu District, Guangzhou 510095, Guangdong Province, China. fangrunya@163.com |
| Key Words |
Gastric cancer; Long intergenic non-protein coding RNA 00657; miR-218-2-3p; Multidrug resistance; Molecular mechanism |
| Core Tip |
Multidrug resistant (MDR) gastric cancer is one of the most common malignancies of the digestive system with high morbidity and mortality. MiR-218-2-3p expression was verified in gastric cancer tissues of 150 patients by quantitative reverse transcription polymerase chain reaction. Overexpression of miR-218-2-3p was constructed by the lentiviral packaging system to prove the functional importance of miR-218-2-3p. Further experiments have verified that the long intergenic non-protein coding RNA 00657/miR-218-2-3p/cyclin D1 axis promotes MDR in gastric cancer by activating the phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin signal pathway. |
| Citation |
Liao QX, Wang T, He JF, Liu C, Wang GQ, He QJ, Wang J, Zeng LS, Fang RY. Long intergenic non-protein coding RNA 00657/miR-218-2-3p/cyclin D1 axis drives gastric cancer chemoresistance. World J Gastroenterol 2026; In press
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| PDF |
123889-in-press.pdf
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Received |
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2026-06-02 07:58 |
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Peer-Review Started |
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2026-06-02 07:58 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2026-07-23 06:01 |
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Revised |
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2026-08-05 11:05 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-11-02 02:19 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-11-04 10:20 |
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Articles in Press |
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2026-11-04 10:20 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
