Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	123917
DOI	10.4240/wjgs.123917
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Cohort Study
Article Title	Safety and efficacy of 125I radioactive seed strand implantation combined with transjugular intrahepatic portosystemic shunt for portal hypertension accompanied by portal vein tumor thrombus
Manuscript Source	Unsolicited Manuscript
All Author List	Zhen-Hua Fan, Zhen-Dong Yue, Lei Wang, Yi-Fan Wu, Yu Zhang, Qi-Mei Li, Dong-Fang Liu, Xiu-Qi Wang and Cheng-Bin Dong
Funding Agency and Grant Number	Funding Agency Grant Number Scientific Research and Development Program of China State Railway Group J2023Z609 Youth Basic Science Foundation Project of Beijing Shijitan Hospital, Capital Medical University 2021-q10
Corresponding Author	Cheng-Bin Dong, MD, PhD, Department of Interventional Radiology, Beijing Shijitan Hospital, Capital Medical University, No. 10 Yangfang Dian Tieyi Road, Haidian District, Beijing 100038, China. doctordcb@sina.com
Key Words	Transjugular intrahepatic portosystemic shunt; Radioactive seed strand; Liver cirrhosis with portal hypertension; 125I radioactive seed; Portal vein tumor thrombus; Hepatocellular carcinoma
Core Tip	This study demonstrates that combining transjugular intrahepatic portosystemic shunt with 125I radioactive seed strand implantation significantly improves survival and reduces stent restenosis in patients with portal hypertension and portal vein tumor thrombus. This combined approach addresses both the hemodynamic consequences of portal hypertension and the oncologic burden of tumor thrombus, representing a paradigm shift toward comprehensive management of this challenging condition.
Citation	Fan ZH, Yue ZD, Wang L, Wu YF, Zhang Y, Li QM, Liu DF, Wang XQ, Dong CB. Safety and efficacy of 125I radioactive seed strand implantation combined with transjugular intrahepatic portosystemic shunt for portal hypertension accompanied by portal vein tumor thrombus. World J Gastrointest Surg 2026; In press DOI: https://doi.org/10.4240/wjgs.123917
PDF	123917-in-press.pdf

Received	2026-06-02 09:16
Peer-Review Started	2026-06-02 09:16
First Decision by Editorial Office Director
Return for Revision	2026-07-17 14:19
Revised	2026-07-31 20:16
Publication Fee Transferred	2026-09-03 15:08
Second Decision by Editor	2026-10-08 07:09
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-10-08 09:48
Articles in Press	2026-10-08 09:48
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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