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Articles in Press
10/12/2026 10:13:49 AM | Browse: 18 | Download: 3
| Category |
Microbiology |
| Manuscript Type |
Meta-Analysis |
| Article Title |
Gut microbiota signatures in colorectal cancer: Evidence synthesis from umbrella review and probiotic intervention studies
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Li-Xuan Zeng, Yu-Chen Jiang, Yi-Qing Wang, Fei Ye, Yue Ouyang, Zi-Ming Zhao, Qi-Biao Wu and Hai-Bo Cheng |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
No. 82361168663 |
| Science and Technology Development Fund, Macau SAR |
No. 0048/2023/AFJ |
| Science and Technology Development Fund, Macau SAR |
No. 0121/2022/A3 |
| Science and Technology Development Fund, Macau SAR |
No. 0127/2023/RIA2 |
| Science and Technology Development Fund, Macau SAR |
No. 0003/2025/NRP |
| Science and Technology Development Fund, Macau SAR |
No. 0164/2023/RIA3 |
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| Corresponding Author |
Hai-Bo Cheng, Chief Physician, PhD, Professor, The First Clinical Medical College, Nanjing University of Chinese Medicine, No. 138 Xianlin Road, Nanjing 210023, Jiangsu Province, China. haibocheng@njucm.edu.cn |
| Key Words |
Colorectal cancer; Gut microbiota; Umbrella review; Meta-analysis; Probiotics; Synbiotics; Microbial biomarkers |
| Core Tip |
This study synthesizes gut microbiota signatures in colorectal cancer (CRC) through two complementary components: An umbrella review with second-order meta-analysis of CRC-associated taxa, and a synthesis of probiotic or synbiotic intervention evidence. The key innovation is distinguishing frequently reported taxa from truly stable taxa across studies. The findings also suggest that probiotic or synbiotic interventions may partially reshape CRC-related dysbiosis, but higher-quality clinical evidence is still needed. |
| Citation |
Zeng LX, Jiang YC, Wang YQ, Ye F, Ouyang Y, Zhao ZM, Wu QB, Cheng HB. Gut microbiota signatures in colorectal cancer: Evidence synthesis from umbrella review and probiotic intervention studies. World J Gastroenterol 2026; In press
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| PDF |
124236-in-press.pdf
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Received |
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2026-06-10 08:52 |
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Peer-Review Started |
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2026-06-10 08:52 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2026-06-30 02:29 |
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Revised |
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2026-07-13 18:27 |
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Publication Fee Transferred |
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2026-08-11 08:19 |
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Second Decision by Editor |
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2026-10-12 03:05 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-10-12 10:13 |
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Articles in Press |
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2026-10-12 10:13 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
