Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	124408
DOI	10.4251/wjgo.124408
Country	China

Category	Oncology
Manuscript Type	Review
Article Title	Myeloid-derived suppressor cells across the intestinal inflammation-colorectal cancer continuum: From immune regulation to immune escape
Manuscript Source	Invited Manuscript
All Author List	Qian-Ru Hang, Yuan-Qing Chu, Xue-Lian Wu, Qing-Yuan Zeng, Rong-Peng Chen and Guo-Qiang Wang
Funding Agency and Grant Number
Corresponding Author	Guo-Qiang Wang, MD, Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Guangzhou Medical University, No. 250 Changgang East Road, Haizhu District, Guangzhou 510260, Guangdong Province, China. wgqjyh@126.com
Key Words	Myeloid-derived suppressor cells; Inflammatory bowel disease; Colorectal cancer; Colitis-associated carcinogenesis; Gut microbiota; Tumor immune microenvironment; Microsatellite-stable colorectal cancer; Immune checkpoint blockade resistance
Core Tip	The roles of myeloid-derived suppressor cells change across intestinal inflammation, colitis-associated carcinogenesis, and colorectal cancer. Their interpretation and therapeutic modulation should therefore account for phenotype, suppressive function, subset, tissue compartment, disease stage, and evidence strength rather than assuming uniform benefit or harm.
Citation	Hang QR, Chu YQ, Wu XL, Zeng QY, Chen RP, Wang GQ. Myeloid-derived suppressor cells across the intestinal inflammation-colorectal cancer continuum: From immune regulation to immune escape. World J Gastrointest Oncol 2026; In press DOI: https://doi.org/10.4251/wjgo.124408
PDF	124408-in-press.pdf

Received	2026-06-15 02:11
Peer-Review Started	2026-06-15 02:11
First Decision by Editorial Office Director
Return for Revision	2026-08-25 06:12
Revised	2026-09-05 08:21
Publication Fee Transferred
Second Decision by Editor	2026-11-05 03:30
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-11-05 07:20
Articles in Press	2026-11-05 07:20
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
Open Access	This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright	© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com