| Category |
Radiology, Nuclear Medicine & Medical Imaging |
| Manuscript Type |
Retrospective Study |
| Article Title |
Noninvasive computed tomography-based intratumoral and peritumoral radiomics for preoperative risk stratification of intraductal papillary mucinous neoplasms
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Tian-Ye Liu, Hou-Pu Liu, Hong-Wei Wang, Xin-Yue Wang, Xiao-Meng Yang, Chun-Lin Zhang, Shu-Yuan Huang, Hai-Peng Yu, Guo-Ping Xu, Xiang Zhang, Wen Shen, Hao-Ran Sun, Yan Sun, Jia-Xin Liu, Xiu-Chao Wang, Sun-Yi Zheng, Zhao-Xiang Ye, Xiao-Nan Cui and Ji-Hui Hao |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Key Laboratory of Druggability Evaluation and Systematic Translational Medicine |
No. 24ZXZSSS00440 |
| Independent Project of the Key Laboratory of Drug Efficacy Evaluation and Systematic Translational Medicine, Tianjin Medical University Cancer Institute and Hospital |
No. QZ23-11 |
| National Natural Science Foundation of China |
No. 82302180 |
|
| Corresponding Author |
Ji-Hui Hao, Pancreas Center, National Clinical Research Center for Cancer, Tianjin’s Clinical Research Center for Cancer, State Key Laboratory of Druggability Evaluation and Systematic Translational Medicine, Tianjin Key Laboratory of Digestive Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute and Hospital, Huan-Hu-Xi Road, Ti-Yuan-Bei, Hexi District, Tianjin 300060, China. haojihui@tjmuch.com |
| Key Words |
Intraductal papillary mucinous neoplasm; Radiomics; Peritumoral radiomics; Computed tomography; Invasive carcinoma |
| Core Tip |
This multicenter study developed a multimodal fusion model integrating computed tomography semantic and multi-regional radiomic features for precise intraductal papillary mucinous neoplasms (IPMNs) risk stratification. Mapping macroscopic alterations and subvisual phenotypes significantly improved malignancy detection. This non-invasive tool refines clinical triage, mitigating unnecessary pancreatectomies for low-grade dysplasia while guiding timely surgery for IPMN-associated invasive carcinoma. |
| Citation |
Liu TY, Liu HP, Wang HW, Wang XY, Yang XM, Zhang CL, Huang SY, Yu HP, Xu GP, Zhang X, Shen W, Sun HR, Sun Y, Liu JX, Wang XC, Zheng SY, Ye ZX, Cui XN, Hao JH. Noninvasive computed tomography-based intratumoral and peritumoral radiomics for preoperative risk stratification of intraductal papillary mucinous neoplasms. World J Gastroenterol 2026; In press
|
| PDF |
124555-in-press.pdf
|
