Publication Name	World Journal of Radiology
Manuscript ID	125041
DOI	10.4329/wjr.125041
Country	China

Category	Radiology, Nuclear Medicine & Medical Imaging
Manuscript Type	Review
Article Title	High-resolution computed tomography assessment of connective tissue disease-associated interstitial lung disease: Advances in diagnosis and prognostic evaluation
Manuscript Source	Invited Manuscript
All Author List	Si-Yu Jiang, Kai-Xiang Su, Cai-Feng Pang, Yu-Qing Tang, Yu-Jie Xiang, Ju Han, Yong-Long He and Rui Li
Funding Agency and Grant Number	Funding Agency Grant Number Sichuan Medical Association Medical Research Projects S20250027 the Health Commission of the Sichuan Province Medical Science and Technology Program 24WXXT10
Corresponding Author	Rui Li, Professor, Department of Radiology, The Affiliated Hospital of North Sichuan Medical College, Maoyuan South Road, Shunqing District, Nanchong 637000, Sichuan Province, China. ddtwg_nsmc@163.com
Key Words	Connective tissue disease-associated interstitial lung disease; High-resolution computed tomography; Semiquantitative scoring; Quantitative computed tomography; Radiomics; Machine learning
Core Tip	This narrative review summarizes current advances in high-resolution computed tomography (CT)-based assessment of connective tissue disease-associated interstitial lung disease across diagnosis, prognostic assessment, and longitudinal monitoring. Visual interpretation and semiquantitative scoring remain the established foundation of clinical practice, whereas quantitative CT provides an emerging objective adjunct. Radiomics, machine learning, and deep learning offer promising capabilities but remain predominantly investigational. We propose a layered, complementary framework that reflects current clinical readiness rather than a validated clinical pathway and highlight key priorities for future translation, including standardization, reproducibility, multicenter validation, harmonized endpoints, and demonstration of clinical utility.
Citation	Jiang SY, Su KX, Pang CF, Tang YQ, Xiang YJ, Han J, He YL, Li R. High-resolution computed tomography assessment of connective tissue disease-associated interstitial lung disease: Advances in diagnosis and prognostic evaluation. World J Radiol 2026; In press DOI: https://doi.org/10.4329/wjr.125041
PDF	125041-in-press.pdf

Received	2026-07-01 00:11
Peer-Review Started	2026-07-01 00:11
First Decision by Editorial Office Director
Return for Revision	2026-08-17 07:33
Revised	2026-08-26 14:14
Publication Fee Transferred
Second Decision by Editor	2026-09-24 08:15
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-09-24 08:29
Articles in Press	2026-09-24 08:29
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1949-8470 (online)
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Copyright	© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
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