BPG is committed to discovery and dissemination of knowledge
Articles in Press
11/5/2026 8:01:45 AM | Browse: 8 | Download: 0
Publication Name World Journal of Psychiatry
Manuscript ID 125242
DOI 10.5498/wjp.125242
Country China
Category Psychology
Manuscript Type Retrospective Cohort Study
Article Title Discharge biomarkers and probable posttraumatic stress symptoms in intensive care unit survivors: A retrospective cohort study
Manuscript Source Unsolicited Manuscript
All Author List Xiao-Xiao Hu, Ru-Ru Zhou, Yu-Jie Xie, Fang-Fang Chen and Zhan-Ling Zhang
Funding Agency and Grant Number
Funding Agency Grant Number
Wenzhou Municipal Science and Technology Project No. YC20250265
Corresponding Author Zhan-Ling Zhang, Department of Intensive Care Unit, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou Medical University, Nanbaixiang Subdistrict, Ouhai District, Wenzhou 325000, Zhejiang Province, China. zzl-1939@163.com
Key Words Probable post-traumatic stress symptoms; Intensive care survivors; Post-intensive care syndrome; Impact of Event Scale-Revised; Cortisol; Interleukin-6; C-reactive protein; Risk prediction; Retrospective cohort study
Core Tip This retrospective single-center cohort examined intensive care unit-discharge cortisol, interleukin-6, and C-reactive protein in relation to subsequent Impact of Event Scale-Revised screening positivity for probable post-traumatic stress symptoms. Seventy-two of 186 survivors screened positive at least once during available follow-up. The combined three-biomarker model had an apparent same-sample area under the receiver operating characteristic curve of 0.884, but the model was not internally optimism-corrected or externally validated. Incomplete visit-level follow-up and inconsistent source analyses preclude interpreting the findings as a definitive incidence estimate or a clinically ready risk-stratification tool.
Citation Hu XX, Zhou RR, Xie YJ, Chen FF, Zhan ZL. Discharge biomarkers and probable posttraumatic stress symptoms in intensive care unit survivors: A retrospective cohort study. World J Psychiatry 2026; In press
PDF 125242-in-press.pdf
Received
2026-07-10 11:04
Peer-Review Started
2026-07-10 11:04
First Decision by Editorial Office Director
Return for Revision
2026-08-03 07:13
Revised
2026-09-03 04:37
Publication Fee Transferred
Second Decision by Editor
2026-11-05 03:30
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-11-05 08:01
Articles in Press
2026-11-05 08:01
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2220-3206 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com